概述

  • 产品名称
    Anti-Mucin 5AC抗体[45M1]
    参阅全部 Mucin 5AC 一抗
  • 描述
    小鼠单克隆抗体[45M1] to Mucin 5AC
  • 宿主
    Mouse
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse, Rabbit, Chicken, Cat, Pig, Monkey不与反应: Cow
  • 免疫原

    Tissue, cells or virus corresponding to Human Mucin 5AC. (M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient).

  • 表位
    The epitope is located in the C-terminal cysteine rich part of the peptide core of Mucin 5AC.
  • 阳性对照
    • IHC-P: Human stomach and gastric carcinoma tissue; Rat stomach tissue.

性能

应用

Our Abpromise guarantee covers the use of ab233936 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Incubate with primary antibody for 30 minutes at room temperature.

靶标

  • 相关性
    Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.
  • 细胞定位
    Secreted; Cytoplasmic and cell surface
  • 数据库链接
  • 别名
    • Apomucin antibody
    • Apomucin Major Airway Glycoprotein antibody
    • Gastric mucin antibody
    • LeB antibody
    • Lewis B blood group antigen antibody
    • Major Airway Glycoprotein antibody
    • MUC 5 antibody
    • MUC5 antibody
    • MUC5AC antibody
    • Mucin 5 subtype AC tracheobronchial antibody
    • Mucin 5 Subtypes A And C antibody
    • Mucin 5 subtypes A and C tracheobronchial/gastric antibody
    • Mucin 5, tracheobronchial/gastric antibody
    • Mucin 5AC antibody
    • Mucin 5AC oligomeric mucus/gel forming antibody
    • Mucin 5AC, oligomeric mucus/gel forming pseudogene antibody
    • Mucin antibody
    • TBM antibody
    • Tracheobronchial Mucin (TBM) antibody
    • Tracheobronchial mucin antibody
    see all

图片

  • Formalin-fixed, paraffin-embedded human stomach tissue stained for Mucin 5AC using ab233936 at 2 μg/ml in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human gastric carcinoma tissue stained for Mucin 5AC using ab233936 at 2 μg/ml in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded rat stomach tissue stained for Mucin 5AC using ab233936 at 2 μg/ml in immunohistochemical analysis.

文献

ab233936 has not yet been referenced specifically in any publications.

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