Anti-MMP3抗体[SL-1 ID3] (ab3204)
Key features and details
- Mouse monoclonal [SL-1 ID3] to MMP3
- Suitable for: ELISA
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-MMP3抗体[SL-1 ID3]
参阅全部 MMP3 一抗 -
描述
小鼠单克隆抗体[SL-1 ID3] to MMP3 -
宿主
Mouse -
特异性
ab3204 reacts with both pro and active forms of MMP 3. -
经测试应用
适用于: ELISAmore details
不适用于: IHC-P -
种属反应性
与反应: Human -
免疫原
APMA (4 Aminophenylmercuric acetate) activated Human stromelysin 1 (SL 1).
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阳性对照
- Conditioned serum-free medium from TPA treated human Endometrial cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
SL-1 ID3 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use at an assay dependent concentration. |
靶标
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功能
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. -
序列相似性
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains. -
结构域
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. -
细胞定位
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 4314 Human
- Omim: 185250 Human
- SwissProt: P08254 Human
- Unigene: 375129 Human
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别名
- CHDS6 antibody
- Matrix metalloproteinase 3 antibody
- Matrix metalloproteinase 3 preproprotein antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab3204 被引用在 1 文献中.
- Wang L et al. Berberine inhibits the ischemia-reperfusion injury induced inflammatory response and apoptosis of myocardial cells through the phosphoinositide 3-kinase/RAC-a serine/threonine-protein kinase and nuclear factor-?B signaling pathways. Exp Ther Med 15:1225-1232 (2018). PubMed: 29403554