Anti-Mesothelioma抗体[HBME-1] (ab2383)

Submit a review Q&A (1)References (1)

Key features and details

  • Mouse monoclonal [HBME-1] to Mesothelioma
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgM

概述

  • 产品名称

    Anti-Mesothelioma抗体[HBME-1]
    参阅全部 Mesothelioma 一抗

  • 描述

    小鼠单克隆抗体[HBME-1] to Mesothelioma

  • 宿主

    Mouse

  • 特异性

    This antibody reacts with an unknown antigen on microvilli of mesothelioma cells. It stains normal mesothelial cells as well as epithelial mesothelimias in a thick membrane pattern due to abundant lung microvilli on the surface of these cells.

  • 经测试应用

    适用于: IHC-Pmore details

  • 种属反应性

    与反应: Human

  • 免疫原

    Suspension of human mesothelioma cells from patients with malignant epithelial mesothelioma.

  • 阳性对照

    • Mesothelioma.

  • 常规说明

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

性能

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • 存储溶液

    Preservative: 0.05% Sodium azide
    Constituent: 1% BSA
  • Concentration information loading...

  • 纯度

    Purified IgM

  • 克隆

    单克隆

  • 克隆编号

    HBME-1

  • 骨髓瘤

    unknown

  • 同种型

    IgM

  • 轻链类型

    unknown

  • 研究领域

应用

Our Abpromise guarantee covers the use of ab2383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC: This antibody may be diluted to a titer of 1:12-1:25 in an ABC method.
    We suggest an incubation period of 60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.
    Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.

    • 靶标

    • 相关性

      Mesothelioma is a rare form of carcinoma of the mesothelial cells which that normally line the body cavities, including the pleura, peritoneum, pericardium, and testis. It may be localized or diffuse. Most, but not all, cases of pleural malignant mesothelioma are associated with asbestos exposure.

    • 别名

      • Malignant mesothelioma susceptibility to antibody
      • MMS antibody

    图片

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
      ab2383 staining human mesothelioma by IHC-P.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
      Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human mesothelioma tissue, staining Mesothelioma with ab2383.

    文献 (1)

    发表研究结果有使用 ab2383？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab2383 被引用在 1 文献中.

    • Chernova T  et al. Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf). Curr Biol 27:3302-3314.e6 (2017). PubMed: 29112861

    客户评价及客户问答

    Show All 评价 Q&A
    提交评价 提交问题

    Question

    What is the concentration of this antibody?

    Read More
    Answer

    Thank you for contacting Abcam regarding ab2383.


    The average concentration of this antibody is 45mg/L. If you have a specific lot number, I can check for that concentration as well.


    I hope this information is helpful. Please do not hesitate to contact us if you have any additional questions.

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com