Anti-Mephalan抗体[MP5/73] (ab97892)
Key features and details
- Rat monoclonal [MP5/73] to Mephalan
- Suitable for: ELISA
- Reacts with: Species independent
- Isotype: IgG2b
概述
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产品名称
Anti-Mephalan抗体[MP5/73] -
描述
大鼠单克隆抗体[MP5/73] to Mephalan -
宿主
Rat -
特异性
This antibody was developed to improve detection of melphalan-DNA adducts through its ability to recognise the stabilised adduct. This antibodiy can be used for quantification of melphalan adducts in purified DNA by ELISA and for immunofluorescent detection of melphalan-DNA adducts in single cells. -
经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Species independent -
免疫原
Full length native protein (purified) corresponding to Mephalan.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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纯度
Protein A/G purified -
克隆
单克隆 -
克隆编号
MP5/73 -
骨髓瘤
Y3/Ag1.2.3 -
同种型
IgG2b -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97892于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent dilution.
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说明 |
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ELISA
Use at an assay dependent dilution. |
靶标
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相关性
Mephalan hydrochloride is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab97892 被引用在 3 文献中.
- Rothbarth J et al. Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo. Biochem Pharmacol 67:1771-8 (2004). PubMed: 15081876
- Frank AJ & Tilby MJ Quantification of DNA adducts in individual cells by immunofluorescence: effects of variation in DNA conformation. Exp Cell Res 283:127-34 (2003). PubMed: 12581733
- Tilby MJ et al. Immunological detection of DNA damage caused by melphalan using monoclonal antibodies. Cancer Res 47:1542-6 (1987). PubMed: 3815354