Anti-MCP1抗体[ECE.2] (ab8101)
Key features and details
- Rat monoclonal [ECE.2] to MCP1
- Suitable for: IHC-Fr
- Reacts with: Mouse
- Isotype: IgG1
概述
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产品名称
Anti-MCP1抗体[ECE.2]
参阅全部 MCP1 一抗 -
描述
大鼠单克隆抗体[ECE.2] to MCP1 -
宿主
Rat -
特异性
The antibody reacts with murine JE / MCP-1. -
经测试应用
适用于: IHC-Frmore details -
种属反应性
与反应: Mouse
不与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Recombinant mouse MCP1 protein (ab9901) can be used as a positive control in WB.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
0.2 µm filtered antibody solution -
克隆
单克隆 -
克隆编号
ECE.2 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
应用 | Ab评论 | 说明 |
---|---|---|
IHC-Fr |
Use at an assay dependent concentration.
|
说明 |
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IHC-Fr
Use at an assay dependent concentration. |
靶标
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功能
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. -
序列相似性
Belongs to the intercrine beta (chemokine CC) family. -
翻译后修饰
Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 20296 Mouse
- SwissProt: P10148 Mouse
- Unigene: 290320 Mouse
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别名
- C-C motif chemokine 2 antibody
- CCL2 antibody
- CCL2_HUMAN antibody
see all
图片
实验方案
数据表及文件
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Datasheet download
文献 (28)
ab8101 被引用在 28 文献中.
- Ling Z et al. Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma. Cell Death Dis 13:158 (2022). PubMed: 35177591
- Trolese MC et al. Boosting the peripheral immune response in the skeletal muscles improved motor function in ALS transgenic mice. Mol Ther 30:2760-2784 (2022). PubMed: 35477657
- Zhang W et al. Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway. Aging (Albany NY) 13:10659-10671 (2021). PubMed: 33770763
- Tong W et al. Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles. Theranostics 11:506-521 (2021). PubMed: 33391489
- Tu W et al. TCF4 enhances hepatic metastasis of colorectal cancer by regulating tumor-associated macrophage via CCL2/CCR2 signaling. Cell Death Dis 12:882 (2021). PubMed: 34580284