Anti-MAP4K4/NIK抗体(ab69885)
Key features and details
- Rabbit polyclonal to MAP4K4/NIK
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MAP4K4/NIK抗体
参阅全部 MAP4K4/NIK 一抗 -
描述
兔多克隆抗体to MAP4K4/NIK -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Synthetic peptide corresponding to Human MAP4K4/NIK (internal sequence).
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阳性对照
- A549 cells. Extracts from COLO and HUVEC cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab69885于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Detects a band of approximately 142 kDa (predicted molecular weight: 142 kDa).
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ICC/IF |
1/500 - 1/1000.
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说明 |
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WB
1/500 - 1/1000. Detects a band of approximately 142 kDa (predicted molecular weight: 142 kDa). |
ICC/IF
1/500 - 1/1000. |
靶标
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功能
Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. -
组织特异性
Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta. -
序列相似性
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 CNH domain.
Contains 1 protein kinase domain. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 9448 Human
- Entrez Gene: 26921 Mouse
- Omim: 604666 Human
- SwissProt: O95819 Human
- SwissProt: P97820 Mouse
- Unigene: 431550 Human
- Unigene: 485049 Mouse
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别名
- FLH21957 antibody
- FLJ10410 antibody
- FLJ20373 antibody
see all
图片
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All lanes : Anti-MAP4K4/NIK antibody (ab69885) at 1/500 dilution
Lane 1 : Extracts from COLO cells
Lane 2 : Extracts from HUVEC cells
Lane 3 : Extracts from HUVEC cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 142 kDa
Observed band size: 142 kDa -
Immunofluorescence analysis of A549 cells using ab69885 at 1/500 dilution, in the presence or absence of the immunising peptide.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab69885 尚未被引用在任何文献中。