Anti-LTBP4抗体(ab222844)
Key features and details
- Rabbit polyclonal to LTBP4
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-LTBP4抗体 -
描述
兔多克隆抗体to LTBP4 -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to Human LTBP4 aa 977-1180.
Database link: Q8N2S1 -
阳性对照
- IHC-P: Human kidney tissue. ICC/IF: HepG2 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Purity >95% -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab222844于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
1/50 - 1/200.
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IHC-P |
1/20 - 1/200.
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说明 |
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ICC/IF
1/50 - 1/200. |
IHC-P
1/20 - 1/200. |
靶标
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功能
May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). -
组织特异性
Highly expressed in heart, skeletal muscle, pancreas, uterus, and small intestine. Weakly expressed in placenta and lung. -
疾病相关
Urban-Rifkin-Davis syndrome -
序列相似性
Belongs to the LTBP family.
Contains 16 EGF-like domains.
Contains 4 TB (TGF-beta binding) domains. -
发展阶段
Very low expression in fetal brain, liver, heart, spleen and thymus. -
翻译后修饰
Contains hydroxylated asparagine residues. -
细胞定位
Secreted, extracellular space, extracellular matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 8425 Human
- Omim: 604710 Human
- SwissProt: Q8N2S1 Human
- Unigene: 466766 Human
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别名
- latent transforming growth factor beta binding protein 4 antibody
- latent transforming growth factor beta binding protein 4L antibody
- Latent-transforming growth factor beta-binding protein 4 antibody
see all
图片
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HepG2 (human liver hepatocellular carcinoma cell line) cells stained for LTBP4 (green) using ab222844 at 1/100 dilution in ICC/IF. Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L) was used as secondary antibody.
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Paraffin-embedded human kidney tissue stained for LTBP4 using ab222844 at 1/100 dilution in immunohistochemical analysis.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab222844 被引用在 1 文献中.
- Jongkamonwiwat N et al. Noise Exposures Causing Hearing Loss Generate Proteotoxic Stress and Activate the Proteostasis Network. Cell Rep 33:108431 (2020). PubMed: 33238128