Anti-liver Arginase抗体(ab60176)
Key features and details
- Goat polyclonal to liver Arginase
- Suitable for: ICC, IHC-Fr, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
-
产品名称
Anti-liver Arginase抗体
参阅全部 Liver Arginase 一抗 -
描述
山羊多克隆抗体to liver Arginase -
宿主
Goat -
经测试应用
适用于: ICC, IHC-Fr, WBmore details -
种属反应性
与反应: Mouse, Rat -
免疫原
Synthetic peptide corresponding to Rat Liver Arginase aa 311-323 (C terminal).
Sequence:C-NHKPETDYLKPPK
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
-
纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Assay kits
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab60176于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC | (2) |
Use at an assay dependent concentration.
|
IHC-Fr | (2) |
Use at an assay dependent concentration.
|
WB | (1) |
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa).
A 1 hour primary incubation at room temperature is recommended for this product. |
说明 |
---|
ICC
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. |
WB
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa). A 1 hour primary incubation at room temperature is recommended for this product. |
靶标
-
通路
Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. -
疾病相关
Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia. -
序列相似性
Belongs to the arginase family. -
细胞定位
Cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 11846 Mouse
- Entrez Gene: 29221 Rat
- SwissProt: Q61176 Mouse
- SwissProt: P07824 Rat
- Unigene: 154144 Mouse
- Unigene: 9857 Rat
-
别名
- A I antibody
- Al antibody
- ARG 1 antibody
see all
图片
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (34)
ab60176 被引用在 34 文献中.
- Li J et al. S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy. Nat Commun 13:1481 (2022). PubMed: 35304461
- Zhou J et al. Magnetic resonance imaging of tumor-associated-macrophages (TAMs) with a nanoparticle contrast agent. RSC Adv 12:7742-7756 (2022). PubMed: 35424752
- Sun SJ et al. Repeated intravenous administration of hiPSC-MSCs enhance the efficacy of cell-based therapy in tissue regeneration. Commun Biol 5:867 (2022). PubMed: 36008710
- Lang GP et al. Rutin pretreatment promotes microglial M1 to M2 phenotype polarization. Neural Regen Res 16:2499-2504 (2021). PubMed: 33907040
- Ji WH et al. Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period. Front Immunol 12:763067 (2021). PubMed: 34712245