Anti-Kallikrein 5抗体(ab28565)
Key features and details
- Rabbit polyclonal to Kallikrein 5
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
概述
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产品名称
Anti-Kallikrein 5抗体
参阅全部 Kallikrein 5 一抗 -
描述
兔多克隆抗体to Kallikrein 5 -
宿主
Rabbit -
特异性
This antibody reacts with Kallikrein 5, but does not react with the other Kallikreins (1-7 and 9-15). -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Synthetic peptide based on the Kallikrein loop area of human Kallikrein 5.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 50% Glycerol -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab28565于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/5000. Predicted molecular weight: 32 kDa. 1/1000 (when using colorimetric substrates such as BCIP/NBT)- 1/5000 (chemiluminescent substrates). Dilution optimised using Chromogenic detection.
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说明 |
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WB
1/1000 - 1/5000. Predicted molecular weight: 32 kDa. 1/1000 (when using colorimetric substrates such as BCIP/NBT)- 1/5000 (chemiluminescent substrates). Dilution optimised using Chromogenic detection. |
靶标
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功能
May be involved in desquamation. -
组织特异性
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin. -
序列相似性
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
细胞定位
Secreted. - Information by UniProt
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别名
- HK5 antibody
- Kallikrein 5 antibody
- Kallikrein L2 antibody
see all
图片
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All lanes : Anti-Kallikrein 5 antibody (ab28565) at 1/1000 dilution
Lane 1 : Kallikrein 5 at 0.05 µg
Lane 2 : Kallikrein 5 at 0.01 µg
Lane 3 : Kallikrein 5 at 0.001 µg
Predicted band size: 32 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab28565 被引用在 5 文献中.
- Alves MG et al. Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma. Transl Oncol 14:100970 (2021). PubMed: 33260070
- Abuduhadeer X et al. Clinical significance of kallikrein 5 as a novel prognostic biomarker in gastric adenocarcinoma. J Clin Lab Anal 35:e23958 (2021). PubMed: 34510543
- Jiang R et al. Kallikrein-5 promotes cleavage of desmoglein-1 and loss of cell-cell cohesion in oral squamous cell carcinoma. J Biol Chem 286:9127-35 (2011). ICC/IF ; Human . PubMed: 21163944
- Ghosh S et al. Urinary-type plasminogen activator receptor/alpha 3 beta 1 integrin signaling, altered gene expression, and oral tumor progression. Mol Cancer Res 8:145-58 (2010). IHC-P ; Mouse . PubMed: 20145038
- Pettus JR et al. Multiple kallikrein (KLK 5, 7, 8, and 10) expression in squamous cell carcinoma of the oral cavity. Histol Histopathol 24:197-207 (2009). PubMed: 19085836