Key features and details
- Rabbit polyclonal to Kallikrein 5
- Isotype: IgG
参阅全部 Kallikrein 5 一抗
描述兔多克隆抗体to Kallikrein 5
Synthetic peptide, corresponding to amino acids 280-293 of Human KLK5.
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Concentration information loading...
纯度Immunogen affinity purified
功能May be involved in desquamation.
组织特异性Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin.
序列相似性Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
- Information by UniProt
- HK5 antibody
- Kallikrein 5 antibody
- Kallikrein L2 antibody
ab7283 被引用在 4 文献中.
- Furio L et al. Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome. J Exp Med 211:499-513 (2014). PubMed: 24534191
- Bonnart C et al. Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing. J Clin Invest 120:871-82 (2010). IHC-P ; Human . PubMed: 20179351
- Yanagi T et al. Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice. Am J Pathol 177:106-18 (2010). WB, IHC-P ; Mouse . PubMed: 20489143
- Di WL et al. A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins. Br J Dermatol 161:404-12 (2009). WB ; Human . PubMed: 19438860