Key features and details
- Rabbit polyclonal to Kallikrein 11
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
参阅全部 Kallikrein 11 一抗
描述兔多克隆抗体to Kallikrein 11
经测试应用适用于: WB, IHC-Pmore details
Synthetic peptide corresponding to a sequence at the C terminal of Human Kallikrein 11.
- Human prostatic cancer tissue; M231, M453, Jurkat, COLO320 and HT1080 cell lysates.
存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
存储溶液Preservatives: 0.025% Sodium azide, 0.025% Thimerosal (merthiolate)
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
纯度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab131038 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 31 kDa.|
|IHC-P||Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
功能Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.
组织特异性Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level).
序列相似性Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
翻译后修饰About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected by plasminogen.
- Information by UniProt
- Hippostasin antibody
- hK11 antibody
- Kallikrein 11 antibody
All lanes : Anti-Kallikrein 11 antibody (ab131038) at 0.1 µg/ml
Lane 1 : M231 cell lysate
Lane 2 : M453 cell lysate
Lane 3 : Jurkat cell lysate
Lane 4 : COLO320 cell lysate
Lane 5 : HT1080 cell lysate
Lane 6 : COLO320 Cell Lysate
Lane 7 : JURKAT Cell Lysate
Predicted band size: 31 kDa
Immunohistochemical analysis of paraffin-embedded Human prostatic cancer tissue labelling Kallikrein 11 with ab131038 at 0.5 µg/ml.
ab131038 被引用在 1 文献中.
- Geng X et al. Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients. Am J Cancer Res 8:1856-1864 (2018). PubMed: 30323977