Key features and details
- Rabbit polyclonal to JMJD1C
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
经测试应用适用于: IHC-P, WBmore details
Synthetic peptide, corresponding to a region within amino acids 150-200 of Human JMJD1C (NP_004232.2).
- HeLa and 293T whole cell lysates.
存放说明Shipped at 4°C. Store at +4°C.
存储溶液Preservative: 0.09% Sodium azide
Constituents: 99% Tris buffered saline, 0.1% BSA
Concentration information loading...
纯度Immunogen affinity purified
纯化说明Purified using an epitope specific to JMJD1C immobilized on solid support.
Our Abpromise guarantee covers the use of ab130922 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|WB||1/2000 - 1/10000. Predicted molecular weight: 284 kDa.|
功能Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes.
序列相似性Belongs to the JHDM2 histone demethylase family.
Contains 1 JmjC domain.
结构域Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
- JHD2C_HUMAN antibody
- Jmjd1c antibody
- Jumonji domain containing 1C antibody
All lanes : Anti-JMJD1C antibody (ab130922) at 0.04 µg/ml
Lane 1 : HeLa whole cell lysate at 50 µg
Lane 2 : HeLa whole cell lysate at 15 µg
Lane 3 : HeLa whole cell lysate at 5 µg
Lane 4 : 293T whole cell lysate at 15 µg
Developed using the ECL technique.
Predicted band size: 284 kDa
Exposure time: 3 minutes
ab130922 被引用在 1 文献中.
- Li CH et al. Expression pattern of JMJD1C in oocytes and its impact on early embryonic development. Genet Mol Res 14:18249-58 (2015). PubMed: 26782472