Anti-JMJD1C抗体(ab130922)

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Key features and details

  • Rabbit polyclonal to JMJD1C
  • Suitable for: IHC-P, WB
  • Reacts with: Human
  • Isotype: IgG

概述

  • 产品名称

    Anti-JMJD1C抗体

  • 描述

    兔多克隆抗体to JMJD1C

  • 宿主

    Rabbit

  • 经测试应用

    适用于: IHC-P, WBmore details
    不适用于: IP

  • 种属反应性

    与反应: Human

  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 150-200 of Human JMJD1C (NP_004232.2).

  • 阳性对照

    • HeLa and 293T whole cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab130922 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
WB 1/2000 - 1/10000. Predicted molecular weight: 284 kDa.
  • 应用说明
    Is unsuitable for IP.

    • 靶标

    • 功能

      Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes.

    • 序列相似性

      Belongs to the JHDM2 histone demethylase family.
      Contains 1 JmjC domain.

    • 结构域

      Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.

    • 翻译后修饰

      Phosphorylated upon DNA damage, probably by ATM or ATR.

    • 细胞定位

      Nucleus.
    • Information by UniProt

    • 数据库链接

      • 别名

        • JHD2C_HUMAN antibody
        • Jmjd1c antibody
        • Jumonji domain containing 1C antibody
        • Jumonji domain-containing protein 1C antibody
        • Probable JmjC domain-containing histone demethylation protein 2C antibody
        • Thryoid receptor interacting protein antibody
        • Thyroid receptor-interacting protein 8 antibody
        • TR-interacting protein 8 antibody
        • TRIP-8 antibody
        • TRIP8 antibody
        see all

      图片

      • Western blot - Anti-JMJD1C antibody (ab130922)
        Western blot - Anti-JMJD1C antibody (ab130922)
        All lanes : Anti-JMJD1C antibody (ab130922) at 0.04 µg/ml

        Lane 1 : HeLa whole cell lysate at 50 µg
        Lane 2 : HeLa whole cell lysate at 15 µg
        Lane 3 : HeLa whole cell lysate at 5 µg
        Lane 4 : 293T whole cell lysate at 15 µg

        Developed using the ECL technique.

        Predicted band size: 284 kDa


        Exposure time: 3 minutes

      文献

      发表研究结果有使用 ab130922？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab130922 被引用在 1 文献中.

      • Li CH  et al. Expression pattern of JMJD1C in oocytes and its impact on early embryonic development. Genet Mol Res 14:18249-58 (2015). PubMed: 26782472

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