Anti-JMJD1C抗体(ab130922)
Key features and details
- Rabbit polyclonal to JMJD1C
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-JMJD1C抗体 -
描述
兔多克隆抗体to JMJD1C -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide, corresponding to a region within amino acids 150-200 of Human JMJD1C (NP_004232.2).
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阳性对照
- HeLa and 293T whole cell lysates.
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常规说明
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.09% Sodium azide
Constituents: 99% Tris buffered saline, 0.1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
Purified using an epitope specific to JMJD1C immobilized on solid support. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
Our Abpromise guarantee covers the use of ab130922 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | 1/2000 - 1/10000. Predicted molecular weight: 284 kDa. |
靶标
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功能
Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes. -
序列相似性
Belongs to the JHDM2 histone demethylase family.
Contains 1 JmjC domain. -
结构域
Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 221037 Human
- NCBI: NP_004232.2 Human
- Omim: 604503 Human
- SwissProt: Q15652 Human
- Unigene: 413416 Human
- Unigene: 499821 Human
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别名
- JHD2C_HUMAN antibody
- Jmjd1c antibody
- Jumonji domain containing 1C antibody
see all
图片
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Western blot - Anti-JMJD1C antibody (ab130922)All lanes : Anti-JMJD1C antibody (ab130922) at 0.04 µg/ml
Lane 1 : HeLa whole cell lysate at 50 µg
Lane 2 : HeLa whole cell lysate at 15 µg
Lane 3 : HeLa whole cell lysate at 5 µg
Lane 4 : 293T whole cell lysate at 15 µg
Developed using the ECL technique.
Predicted band size: 284 kDa
Exposure time: 3 minutes
数据表及文件
文献 (1)
ab130922 被引用在 1 文献中.
- Li CH et al. Expression pattern of JMJD1C in oocytes and its impact on early embryonic development. Genet Mol Res 14:18249-58 (2015). PubMed: 26782472
