Anti-ITPR2抗体(ab5805)

Submit a review Submit a question References (3)

Key features and details

  • Rabbit polyclonal to ITPR2
  • Suitable for: IHC-Fr
  • Reacts with: Mouse, Rat, Human, Amphibian, Salamander
  • Isotype: IgG

概述

  • 产品名称

    Anti-ITPR2抗体
    参阅全部 ITPR2 一抗

  • 描述

    兔多克隆抗体to ITPR2

  • 宿主

    Rabbit

  • 经测试应用

    适用于: IHC-Frmore details
    不适用于: WB

  • 种属反应性

    与反应: Mouse, Rat, Human, Amphibian, Salamander
    预测可用于: Cow

  • 免疫原

    Synthetic peptide corresponding to Rat ITPR2 aa 317-334.
    Sequence:

    ELNPDYRDAQNEGKTVRD


    (Peptide available as ab5842)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • 常规说明

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

性能

应用

Our Abpromise guarantee covers the use of ab5805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/100.
  • 应用说明
    Is unsuitable for WB.

    • 靶标

    • 功能

      Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.

    • 组织特异性

      Isoform Short is found in skeletal muscle and heart.

    • 疾病相关

      Anhidrosis, isolated, with normal sweat glands

    • 序列相似性

      Belongs to the InsP3 receptor family.
      Contains 5 MIR domains.

    • 结构域

      The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

    • 翻译后修饰

      Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.

    • 细胞定位

      Endoplasmic reticulum membrane.
    • Information by UniProt

    • 数据库链接

      see all

    • 别名

      • 4 antibody
      • 5-trisphosphate receptor antibody
      • Inositol 1 4 5 trisphosphate receptor type 2 antibody
      • Inositol 1,4,5-trisphosphate receptor type 2 antibody
      • Inositol 145 trisphosphate receptor type 2 antibody
      • InsP3 R2 antibody
      • InsP3R2 antibody
      • IP3 R2 antibody
      • IP3 receptor antibody
      • IP3 receptor isoform 2 antibody
      • IP3R 2 antibody
      • IP3R2 antibody
      • ITPR 2 antibody
      • Itpr2 antibody
      • ITPR2_HUMAN antibody
      • Type 2 inositol 1 4 5 trisphosphate receptor antibody
      • Type 2 inositol 1 antibody
      • Type 2 inositol 145 trisphosphate receptor antibody
      • Type 2 InsP3 receptor antibody
      see all

    图片

    • Immunohistochemistry (Frozen sections) - Anti-ITPR2 antibody (ab5805)
      Immunohistochemistry (Frozen sections) - Anti-ITPR2 antibody (ab5805)
      Shows immunolocalization of IP3R-II in rat brain using ab5805.

    文献 (3)

    发表研究结果有使用 ab5805？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab5805 被引用在 3 文献中.

    • Jaiswal PK  et al. Biochemical characteristics of the chondrocyte-enriched SNORC protein and its transcriptional regulation by SOX9. Sci Rep 10:7790 (2020). PubMed: 32385306
    • Causton B  et al. CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata. Am J Respir Cell Mol Biol 59:684-694 (2018). PubMed: 29958012
    • Okamoto Y  et al. Arrhythmogenic coupling between the Na+ -Ca2+ exchanger and inositol 1,4,5-triphosphate receptor in rat pulmonary vein cardiomyocytes. J Mol Cell Cardiol 52:988-97 (2012). ICC/IF ; Rat . PubMed: 22285480

    客户评价及客户问答

    Show All 评价 Q&A
    提交评价 提交问题

    There are currently no Customer reviews or Questions for ab5805.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com