Anti-ITPR2抗体(ab5805)

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Key features and details

  • Rabbit polyclonal to ITPR2
  • Suitable for: IHC-Fr
  • Reacts with: Mouse, Rat, Human, Amphibian, Salamander
  • Isotype: IgG

概述

  • 产品名称

    Anti-ITPR2抗体
    参阅全部 ITPR2 一抗

  • 描述

    兔多克隆抗体to ITPR2

  • 宿主

    Rabbit

  • 经测试应用

    适用于: IHC-Frmore details
    不适用于: WB

  • 种属反应性

    与反应: Mouse, Rat, Human, Amphibian, Salamander
    预测可用于: Cow

  • 免疫原

    Synthetic peptide corresponding to Rat ITPR2 aa 317-334.
    Sequence:

    ELNPDYRDAQNEGKTVRD


    (Peptide available as ab5842)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

性能

应用

Our Abpromise guarantee covers the use of ab5805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/100.
  • 应用说明
    Is unsuitable for WB.

    • 靶标

    • 功能

      Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.

    • 组织特异性

      Isoform Short is found in skeletal muscle and heart.

    • 疾病相关

      Anhidrosis, isolated, with normal sweat glands

    • 序列相似性

      Belongs to the InsP3 receptor family.
      Contains 5 MIR domains.

    • 结构域

      The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

    • 翻译后修饰

      Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.

    • 细胞定位

      Endoplasmic reticulum membrane.
    • Information by UniProt

    • 数据库链接

      see all

    • 别名

      • 4 antibody
      • 5-trisphosphate receptor antibody
      • Inositol 1 4 5 trisphosphate receptor type 2 antibody
      • Inositol 1,4,5-trisphosphate receptor type 2 antibody
      • Inositol 145 trisphosphate receptor type 2 antibody
      • InsP3 R2 antibody
      • InsP3R2 antibody
      • IP3 R2 antibody
      • IP3 receptor antibody
      • IP3 receptor isoform 2 antibody
      • IP3R 2 antibody
      • IP3R2 antibody
      • ITPR 2 antibody
      • Itpr2 antibody
      • ITPR2_HUMAN antibody
      • Type 2 inositol 1 4 5 trisphosphate receptor antibody
      • Type 2 inositol 1 antibody
      • Type 2 inositol 145 trisphosphate receptor antibody
      • Type 2 InsP3 receptor antibody
      see all

    图片

    • Immunohistochemistry (Frozen sections) - Anti-ITPR2 antibody (ab5805)
      Immunohistochemistry (Frozen sections) - Anti-ITPR2 antibody (ab5805)
      Shows immunolocalization of IP3R-II in rat brain using ab5805.

    文献 (2)

    发表研究结果有使用 ab5805？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab5805 被引用在 2 文献中.

    • Causton B  et al. CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata. Am J Respir Cell Mol Biol 59:684-694 (2018). PubMed: 29958012
    • Okamoto Y  et al. Arrhythmogenic coupling between the Na+ -Ca2+ exchanger and inositol 1,4,5-triphosphate receptor in rat pulmonary vein cardiomyocytes. J Mol Cell Cardiol 52:988-97 (2012). ICC/IF ; Rat . PubMed: 22285480

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