重组Anti-IRX1抗体[EPR13139] (ab180860)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR13139] to IRX1
- Suitable for: WB, IP
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-IRX1抗体[EPR13139]
参阅全部 IRX1 一抗 -
描述
兔单克隆抗体[EPR13139] to IRX1 -
宿主
Rabbit -
经测试应用
适用于: WB, IPmore details
不适用于: ICC/IF or IHC-P -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human IRX1 aa 50-150 (Cysteine residue). The exact sequence is proprietary.
Database link: P78414 -
阳性对照
- Human stomach, small intestine and fetal heart lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR13139 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180860于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 50 kDa.
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IP |
1/10 - 1/100.
|
说明 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 50 kDa. |
IP
1/10 - 1/100. |
靶标
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相关性
IRX1 is a member of the Iroquois homeobox gene family. The genes from this family have multiple roles in vertebrate development. The gene encoding IRX1 is expressed in the brain, lung and gut during specific stages of mouse development. -
细胞定位
Nuclear -
数据库链接
- Entrez Gene: 79192 Human
- Omim: 606197 Human
- SwissProt: P78414 Human
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别名
- Homeodomain protein IRXA1 antibody
- Iroquois Homeobox Protein 1 antibody
- Iroquois-class homeodomain protein IRX-1 antibody
see all
图片
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All lanes : Anti-IRX1 antibody [EPR13139] (ab180860) at 1/1000 dilution
Lane 1 : Human stomach lysate
Lane 2 : Human small intestine lysate
Lane 3 : Human fetal heart lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 50 kDa -
Western blot analysis of immunoprecipitation pellet from (1) Human stomach lysate or (2) 1X PBS (negative control) immunoprecipitated using ab180860 at 1/10 dilution; HRP-conjugated anti-Rabbit IgG preferentially detecting the non-reduced form of Rabbit IgG.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab180860 被引用在 2 文献中.
- Zeng L et al. IRX1 hypermethylation promotes heart failure by inhibiting CXCL14 expression. Cell Cycle 18:3251-3262 (2019). PubMed: 31640472
- Zhang P et al. Clinical significance of Iroquois Homeobox Gene - IRX1 in human glioma. Mol Med Rep 17:4651-4656 (2018). PubMed: 29328446