Anti-Integrin beta 5抗体(ab15459)
Key features and details
- Rabbit polyclonal to Integrin beta 5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-Integrin beta 5抗体
参阅全部 Integrin beta 5 一抗 -
描述
兔多克隆抗体to Integrin beta 5 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Hamster -
免疫原
Synthetic peptide within Human Integrin beta 5 aa 750 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P18084 -
常规说明
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab15459于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P | (1) |
1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
|
说明 |
---|
IHC-P
1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
-
功能
Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. -
序列相似性
Belongs to the integrin beta chain family.
Contains 1 PSI domain.
Contains 1 VWFA domain. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 3693 Human
- Entrez Gene: 16419 Mouse
- Entrez Gene: 257645 Rat
- Omim: 147561 Human
- SwissProt: P18084 Human
- SwissProt: O70309 Mouse
- Unigene: 536663 Human
- Unigene: 6424 Mouse
-
别名
- FLJ26658 antibody
- Integrin beta-5 antibody
- Integrin subunit beta 5 antibody
see all
图片
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (28)
ab15459 被引用在 28 文献中.
- Bi J et al. Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin aVß5 receptor. J Cell Mol Med 24:996-1009 (2020). PubMed: 31701659
- Geng H et al. SHCBP1 Promotes Papillary Thyroid Carcinoma Carcinogenesis and Progression Through Promoting Formation of Integrin and Collagen and Maintaining Cell Stemness. Front Endocrinol (Lausanne) 11:613879 (2020). PubMed: 33716952
- Li Y et al. ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM. Front Cell Neurosci 12:489 (2018). PubMed: 30618636
- Lin Z et al. Integrin-ß5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating ß-catenin stability. J Exp Clin Cancer Res 37:17 (2018). PubMed: 29386044
- Chai K et al. Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity. Oncotarget 9:26130-26143 (2018). PubMed: 29899847