APC Anti-IL-2 Receptor alpha抗体[3C7] (ab25485)
Key features and details
- APC Rat monoclonal [3C7] to IL-2 Receptor alpha
- Suitable for: Flow Cyt, IHC-Fr
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2b
概述
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产品名称
APC Anti-IL-2 Receptor alpha抗体[3C7]
参阅全部 IL-2 Receptor alpha 一抗 -
描述
APC大鼠单克隆抗体[3C7] to IL-2 Receptor alpha -
宿主
Rat -
偶联物
APC. Ex: 645nm, Em: 660nm -
特异性
ab25485 recognises low affinity alpha chain IL-2 receptor (MW 55 kDa) (IL-2R alpha). -
经测试应用
适用于: Flow Cyt, IHC-Frmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to IL-2 Receptor alpha. IL-2 dependent BALB/c helper T cell clone HT2
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Store In the Dark. -
存储溶液
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Stabilising agent. -
Concentration information loading...
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纯度
Affinity purified -
克隆
单克隆 -
克隆编号
3C7 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25485于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt |
Use 0.3µg for 106 cells.
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IHC-Fr |
Use at an assay dependent concentration.
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说明 |
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Flow Cyt
Use 0.3µg for 106 cells. |
IHC-Fr
Use at an assay dependent concentration. |
靶标
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功能
Receptor for interleukin-2. -
疾病相关
Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. -
序列相似性
Contains 2 Sushi (CCP/SCR) domains. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 16184 Mouse
- SwissProt: P01590 Mouse
- Unigene: 915 Mouse
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别名
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab25485 被引用在 1 文献中.
- Bursen A et al. The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4. Blood 115:3570-9 (2010). Flow Cyt ; Mouse . PubMed: 20194896