Anti-IL-22RA1抗体(ab5984)
Key features and details
- Rabbit polyclonal to IL-22RA1
- Suitable for: WB, IHC-P, ICC, ICC/IF
- Reacts with: Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-IL-22RA1抗体
参阅全部 IL-22RA1 一抗 -
描述
兔多克隆抗体to IL-22RA1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-P, ICC, ICC/IFmore details -
种属反应性
与反应: Rat, Human -
免疫原
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阳性对照
- WB: HepG2 whole cell lysate (ab7900). IHC-P: Rat kidney tissue. ICC/IF: HepG2 cells. ICC: HepG2 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C. Avoid freeze / thaw cycle. Stable for 12 months at -20°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
IL-22RA1 Antibody is affinity chromatography purified via peptide column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Conjugation kits
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (2) |
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 62 kDa.
|
| IHC-P | (1) |
Use a concentration of 5 µg/ml.
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| ICC |
Use a concentration of 10 µg/ml.
|
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| ICC/IF |
Use a concentration of 10 mg/ml.
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| 说明 |
|---|
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WB
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 62 kDa. |
|
IHC-P
Use a concentration of 5 µg/ml. |
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ICC
Use a concentration of 10 µg/ml. |
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ICC/IF
Use a concentration of 10 mg/ml. |
靶标
- Information by UniProt
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数据库链接
- Entrez Gene: 58985 Human
- Entrez Gene: 362629 Rat
- Omim: 605457 Human
- SwissProt: Q8N6P7 Human
- Unigene: 110915 Human
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别名
- CRF2 9 antibody
- CRF2-9 antibody
- Cytokine receptor class-II member 9 antibody
see all
图片
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Western blot - Anti-IL-22RA1 antibody (ab5984)Lane 1 : Anti-IL-22RA1 antibody (ab5984) at 0.5 µg/ml
Lane 2 : Anti-IL-22RA1 antibody (ab5984) at 1 µg/ml
All lanes : HepG2 cell lysates -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22RA1 antibody (ab5984)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat kidney tissue labelling IL-22RA1 with ab5984 at 5µg/ml.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22RA1 antibody (ab5984)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat kidney tissue labelling IL-22RA1 with ab5984 at 20µg/ml.
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Immunocytochemistry/ Immunofluorescence - Anti-IL-22RA1 antibody (ab5984)Immunocytochemistry/Immunofluorescence analysis of HepG2 cells labelling IL-22RA1 with ab5984 at 10µg/ml.
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Immunocytochemistry - Anti-IL-22RA1 antibody (ab5984)Immunocytochemistry of IL-22R in HepG2 cells with IL-22RA1 antibody at 10 µg/ml.
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Western blot - Anti-IL-22RA1 antibody (ab5984)Western blot analysis of IL-22RA1 expression in human HepG2 cell lysate with ab5984 at 1µg /ml. Western blot analysis of IL-22R expression in human HepG2 cell lysate with ab5984 at 1µg /ml.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (16)
ab5984 被引用在 16 文献中.
- Zhao J et al. Tumor Cells Interleukin-22 Expression Associates with Elevated Tumor-Associated Macrophages Infiltrating and Poor Prognosis in Patients with Breast Cancer. Cancer Biother Radiopharm 36:160-166 (2021). PubMed: 33090014
- Wang HH et al. Interleukin-24 protects against liver injury in mouse models. EBioMedicine 64:103213 (2021). PubMed: 33508745
- Perusina Lanfranca M et al. Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice. Gastroenterology 158:1417-1432.e11 (2020). PubMed: 31843590
- Liu J et al. IL-22/IL-22R1 promotes proliferation and collagen synthesis of MRC-5 cells via the JAK/STAT3 signaling pathway and regulates airway subepithelial fibrosis. Exp Ther Med 20:2148-2156 (2020). PubMed: 32765690
- Takahashi J et al. Interleukin-22 Directly Activates Myocardial STAT3 (Signal Transducer and Activator of Transcription-3) Signaling Pathway and Prevents Myocardial Ischemia Reperfusion Injury. J Am Heart Assoc 9:e014814 (2020). PubMed: 32301368