人MLKL (phospho S358)多肽(ab206929)
Key features and details
- Suitable for: Blocking
描述
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产品名称
人MLKL (phospho S358)多肽
参阅全部 MLKL 蛋白酶 -
Accession
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无动物成分
No -
性质
Synthetic -
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种属
Human -
修饰
phospho T357 + S358
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相关产品
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Corresponding Antibody
技术指标
Our Abpromise guarantee covers the use of ab206929 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Blocking - Blocking peptide for Anti-MLKL (phospho S358) antibody [EPR9514] (ab187091)
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形式
Lyophilized -
补充说明
This is the blocking peptide for ab187091
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C. Avoid freeze / thaw cycle.
Information available upon request.
常规信息
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别名
- 9130019I15Rik
- FLJ34389
- hMLKL
see all -
序列相似性
Belongs to the protein kinase superfamily.
Contains 1 protein kinase domain. -
结构域
The protein kinase domain is predicted to be catalytically inactive. - Information by UniProt
图片
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To learn more about our protein and peptide range click here.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (4)
ab206929 被引用在 4 文献中.
- Fujita Y et al. Enhanced nuclear localization of phosphorylated MLKL predicts adverse events in patients with dilated cardiomyopathy. ESC Heart Fail 9:3435-3451 (2022). PubMed: 35851586
- Bagnjuk K et al. Necroptosis in primate luteolysis: a role for ceramide. Cell Death Discov 5:67 (2019). PubMed: 30774995
- Bailey LJ et al. Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis. Cell Death Dis 8:e2590 (2017). PubMed: 28151467
- Al-Lamki RS et al. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis. Cell Death Dis 7:e2287 (2016). PubMed: 27362805