抗人IgG4 heavy chain抗体[5C7] (ab1930)
Key features and details
- Mouse monoclonal [5C7] to Human IgG4 heavy chain
- Suitable for: ELISA
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
抗人IgG4 heavy chain抗体[5C7] -
描述
小鼠单克隆抗体[5C7] to人IgG4 heavy chain -
宿主
Mouse -
特异性
Subclass-specific for human IgG4. No allotype restriction. Fc-region specific. -
经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Human -
免疫原
Full length native protein (purified) corresponding to Human Human IgG4 heavy chain.
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常规说明
Concentration varies from lot to lot and can be provided on request.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein A purified -
纯化说明
Chromatography on protein A Sepharose -
克隆
单克隆 -
克隆编号
5C7 -
骨髓瘤
Sp2/0 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
Specific antibody titer is 1/100,000 by indirect ELISA.
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| 说明 |
|---|
|
ELISA
Use at an assay dependent concentration. Specific antibody titer is 1/100,000 by indirect ELISA.
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靶标
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相关性
Immunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants. -
细胞定位
Secreted -
数据库链接
- Entrez Gene: 3503 Human
- Omim: 147130 Human
- SwissProt: P01861 Human
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别名
- AU044919 antibody
- Gamma 2b immunoglobulin antibody
- Ig gamma 4 chain C region antibody
see all
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab1930 被引用在 3 文献中.
- Yang F et al. Transcriptome Profiling Reveals B-Lineage Cells Contribute to the Poor Prognosis and Metastasis of Clear Cell Renal Cell Carcinoma. Front Oncol 11:731896 (2021). PubMed: 34485161
- Harlow DE et al. Myelin Proteolipid Protein Complexes with av Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression. J Neurosci 35:12018-32 (2015). PubMed: 26311781
- Medeiros MM et al. Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon. BMC Infect Dis 13:608 (2013). ELISA ; Human . PubMed: 24373342