Anti-HSV1 + HSV2 gD抗体[2C10] (ab6507)
Key features and details
- Mouse monoclonal [2C10] to HSV1 + HSV2 gD
- Suitable for: WB, ELISA, ICC/IF
- Isotype: IgG2a
概述
-
产品名称
Anti-HSV1 + HSV2 gD抗体[2C10] -
描述
小鼠单克隆抗体[2C10] to HSV1 + HSV2 gD -
宿主
Mouse -
经测试应用
适用于: WB, ELISA, ICC/IFmore details -
种属反应性
与反应: Other species -
免疫原
Tissue, cells or virus corresponding to HSV1 + HSV2 gD.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.4 -
Concentration information loading...
-
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
2C10 -
骨髓瘤
NS1/1-Ag4-1 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/10000.
|
|
ELISA |
1/102400.
|
|
ICC/IF |
1/3200 - 1/25600.
1/3,200 (HSV-2) - 1/25,600 (HSV-1). |
说明 |
---|
WB
1/10000. |
ELISA
1/102400. |
ICC/IF
1/3200 - 1/25600. 1/3,200 (HSV-2) - 1/25,600 (HSV-1). |
靶标
-
相关性
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of the herpes virus family, Herpesviridae, which cause infections in humans. They are also called Human Herpes Virus 1 and 2 (HHV-1 and HHV-2) and are neurotropic and neuroinvasive viruses; they enter and hide in the human nervous system, accounting for their durability in the human body. Under a microscope, HSV- 1 and 2 are virtually identical, sharing approximately 50% of their DNA. Both types infect the body's mucosal surfaces, usually the mouth or genitals, and then establish latency in the nervous system. HSV-1 is commonly associated with herpes outbreaks of the face known as cold sores or fever blisters, whereas HSV-2 is more often associated with genital herpes. Herpes simplex viruses (HSV) use multiple and sequential receptors to enter host cells. HSV glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread. -
别名
- Envelope glycoprotein D antibody
- GD antibody
- Glycoprotein D antibody
- US6 antibody
图片
-
Immunocytochemistry/Immunofluorescence analysis of vero cells infected with HSV1 (left) or HSV2 (right) labelled with ab6507.
-
The WB was completed using the HSV-1 Antigen and the HSV-2 Infected Cell Extract at 10 µg/cm
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (13)
ab6507 被引用在 13 文献中.
- Su P et al. High-brightness anterograde transneuronal HSV1 H129 tracer modified using a Trojan horse-like strategy. Mol Brain 13:5 (2020). PubMed: 31931837
- Li F et al. Amentoflavone Inhibits HSV-1 and ACV-Resistant Strain Infection by Suppressing Viral Early Infection. Viruses 11:N/A (2019). PubMed: 31121928
- Criscuolo E et al. Cell-to-Cell Spread Blocking Activity Is Extremely Limited in the Sera of Herpes Simplex Virus 1 (HSV-1)- and HSV-2-Infected Subjects. J Virol 93:N/A (2019). PubMed: 30867302
- Clementi N et al. Entry inhibition of HSV-1 and -2 protects mice from viral lethal challenge. Antiviral Res 143:48-61 (2017). PubMed: 28396205
- Aravantinou M et al. Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in Simian Immunodeficiency Virus (SIV)-Infected Rhesus Macaques. Front Microbiol 8:2342 (2017). ELISA . PubMed: 29259582