Anti-HSD17B4抗体(ab97971)
Key features and details
- Rabbit polyclonal to HSD17B4
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-HSD17B4抗体
参阅全部 HSD17B4 一抗 -
描述
兔多克隆抗体to HSD17B4 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-P, ICC/IFmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat, Guinea pig, Cow, Pig, Zebrafish -
免疫原
Recombinant fragment corresponding to Human HSD17B4 aa 18-231.
Database link: P51659 -
阳性对照
- WB: HeLa, Mouse brain whole cell lysate IHC-P: Human ovarian cancer. ICC/IF: HeLa cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97971于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 80 kDa.
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IHC-P |
1/100 - 1/1000.
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ICC/IF |
1/100 - 1/1000.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 80 kDa. |
IHC-P
1/100 - 1/1000. |
ICC/IF
1/100 - 1/1000. |
靶标
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功能
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. -
组织特异性
Present in many tissues with highest concentrations in liver, heart, prostate and testis. -
通路
Lipid metabolism; fatty acid beta-oxidation. -
疾病相关
D-bifunctional protein deficiency
Perrault syndrome 1 -
序列相似性
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Contains 1 MaoC-like domain.
Contains 1 SCP2 domain. -
细胞定位
Peroxisome. - Information by UniProt
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数据库链接
- Entrez Gene: 3295 Human
- Entrez Gene: 15488 Mouse
- Entrez Gene: 79244 Rat
- Omim: 601860 Human
- SwissProt: P51659 Human
- SwissProt: P51660 Mouse
- SwissProt: P97852 Rat
- Unigene: 406861 Human
see all -
别名
- 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase antibody
- 17 beta HSD 4 antibody
- 17 beta HSD IV antibody
see all
图片
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Paraffin embedded human ovarian cancer tissue stained for HSD17B4 using ab97971 at 1/500 dilution in immunohistochemical analysis.
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HeLa cells stained for HSD17B4 (green) using ab97971 at 1/500 dilution in ICC/IF.
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Anti-HSD17B4 antibody (ab97971) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 80 kDa
7.5% SDS PAGE -
Anti-HSD17B4 antibody (ab97971) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg
Predicted band size: 80 kDa7.5% SDS PAGE
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab97971 被引用在 2 文献中.
- Murdamoothoo D et al. Tenascin-C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression. EMBO Mol Med 13:e13270 (2021). PubMed: 33988305
- Shi X & Fu L Piceatannol inhibits oxidative stress through modification of Nrf2-signaling pathway in testes and attenuates spermatogenesis and steroidogenesis in rats exposed to cadmium during adulthood. Drug Des Devel Ther 13:2811-2824 (2019). PubMed: 31496657