快线抗体 仍未被充份测试和鉴定, 不在质保范围内, 具体请参见 使用条款及细节

概述

  • 产品名称
    Anti-Hornerin抗体
  • 描述
    山羊多克隆抗体to Hornerin

    该产品是 快线抗体,通过亲和纯化得到。对抗原肽有高灵敏度及特异性(ELISA测试)。 Read the terms of use »

  • 宿主
    Goat
  • 种属反应性

    预测可用于: Human
  • 免疫原

    Synthetic peptide:

    C-QYATQHGEYDTLNK

    , corresponding to internal sequence amino acids 17-30 of Human Hornerin

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 0.5% Tris buffered saline
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab78909 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1/32,000.
    WB: Use at a concentration of 0.3 µg/ml. Predicted molecular weight: 282 kDa.
    Preliminary experiments gave an approx 50 kDa band in human skin lysates after 0.3 µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 282 kDa according to NP_001009931.1. The 50 kDa band was successfully blocked by incubation with the immunizing peptide.
  • 靶标

    • 相关性
      Hornerin has similar structural features to those of profilaggrin, an essential protein for keratinization of epidermal tissues. Hornerin may play a role in cornification.
    • 细胞定位
      Cytoplasmic granule. Note: Found in keratohyalin granules in the granular cells of the epidermis
    • 数据库链接
    • 别名
      • 1110033K19Rik antibody
      • AV011854 antibody
      • Intermediate filament protein antibody
      • S100 calcium binding protein A17, pseudogene 1 antibody
      • S100 calcium binding protein A18, pseudogene 1 antibody
      • S100A16 antibody
      • S100a18 antibody
      • S100a18 ps1 antibody
      see all

    实验方案

    文献

    This product has been referenced in:
    • Gutknecht MF  et al. Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity. Nat Commun 8:552 (2017). Read more (PubMed: 28916756) »

    See 1 Publication for this product

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab78909.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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