抗乙型肝炎病毒Surface Antigen抗体[3E7],prediluted (ab859)
Key features and details
- Mouse monoclonal [3E7] to Hepatitis B Virus Surface Antigen, prediluted
- Suitable for: IHC-P, IHC-Fr
- Reacts with: Hepatitis B virus
- Isotype: IgG1
概述
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产品名称
抗乙型肝炎病毒Surface Antigen抗体[3E7],prediluted
参阅全部 Hepatitis B Virus Surface Antigen 一抗 -
描述
小鼠单克隆抗体[3E7] to乙型肝炎病毒Surface Antigen,prediluted -
宿主
Mouse -
特异性
This antibody stains the cytoplasm of antigen-positive liver cells in patients with Type B viral hepatitis. This antibody reacts with the ‘a’ determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues. -
经测试应用
适用于: IHC-P, IHC-Frmore details -
种属反应性
与反应: Hepatitis B virus -
免疫原
BALB/c mice were immunized with purified HBsAG subtype AYW3.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
存储溶液
Preservative: 0.05% Sodium azide
Inert stabilizer -
Concentration information loading...
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克隆
单克隆 -
克隆编号
3E7 -
骨髓瘤
unknown -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab859 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用 | Ab评论 | 说明 |
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IHC-P | ||
IHC-Fr |
说明 |
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No further titration is required.
We suggest an incubation period of 60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
靶标
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相关性
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. -
细胞定位
Virion membrane -
数据库链接
- Entrez Gene: 2703546 Hepatitis B virus
- SwissProt: P03142 Hepatitis B virus
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别名
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab859 尚未被引用在任何文献中。