Key features and details
- Mouse monoclonal [3E7] to Hepatitis B Virus Surface Antigen, prediluted
- Suitable for: IHC-P, IHC-Fr
- Reacts with: Hepatitis B virus
- Isotype: IgG1
参阅全部 Hepatitis B Virus Surface Antigen 一抗
描述小鼠单克隆抗体[3E7] to乙型肝炎病毒Surface Antigen，prediluted
特异性This antibody stains the cytoplasm of antigen-positive liver cells in patients with Type B viral hepatitis. This antibody reacts with the ‘a’ determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues.
经测试应用适用于: IHC-P, IHC-Frmore details
种属反应性与反应: Hepatitis B virus
BALB/c mice were immunized with purified HBsAG subtype AYW3.
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存放说明Shipped at 4°C. Store at +4°C. Do Not Freeze.
存储溶液Preservative: 0.05% Sodium azide
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The Abpromise guarantee
Our Abpromise guarantee covers the use of ab859 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
No further titration is required.
We suggest an incubation period of 60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
相关性Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody