概述
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产品名称抗乙型肝炎病毒Surface Antigen抗体[3E7]，prediluted
参阅全部 Hepatitis B Virus Surface Antigen 一抗 -
描述小鼠单克隆抗体[3E7] to乙型肝炎病毒Surface Antigen，prediluted
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宿主Mouse
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特异性This antibody stains the cytoplasm of antigen-positive liver cells in patients with Type B viral hepatitis. This antibody reacts with the ‘a’ determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues.
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经测试应用适用于: IHC-P, IHC-Frmore details
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种属反应性与反应: Hepatitis B virus
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免疫原
BALB/c mice were immunized with purified HBsAG subtype AYW3.
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C. Do Not Freeze.
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存储溶液Preservative: 0.05% Sodium azide
Inert stabilizer -
Concentration information loading... -
克隆单克隆
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克隆编号3E7
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骨髓瘤unknown
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同种型IgG1
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab859 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | ||
| IHC-Fr |
应用说明
This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections.
No further titration is required.
We suggest an incubation period of 60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
No further titration is required.
We suggest an incubation period of 60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
靶标
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相关性Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
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细胞定位Virion membrane
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数据库链接
- Entrez Gene: 2703546 Hepatitis B virus
- SwissProt: P03142 Hepatitis B virus
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别名
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
文献
ab859 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"