FITC荧光抗乙型肝炎病毒Surface Antigen (Ad/Ay)抗体(ab32914)
Key features and details
- FITC Rabbit polyclonal to Hepatitis B Virus Surface Antigen (Ad/Ay)
- Suitable for: ICC
- Reacts with: Hepatitis B virus
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
概述
-
产品名称
FITC荧光抗乙型肝炎病毒Surface Antigen (Ad/Ay)抗体
参阅全部 Hepatitis B Virus Surface Antigen (Ad/Ay) 一抗 -
描述
FITC荧光兔多克隆抗体to乙型肝炎病毒Surface Antigen (Ad/Ay) -
宿主
Rabbit -
偶联物
FITC. Ex: 493nm, Em: 528nm -
特异性
This antibody recognizes Hepatitis B Surface Antigen, subtypes ad and ay. -
经测试应用
适用于: ICCmore details -
种属反应性
与反应: Hepatitis B virus -
免疫原
Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad and ay.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.1% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
-
纯化说明
This antibody was purified to monospecific FITC. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab32914于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC |
Use at an assay dependent concentration.
|
说明 |
---|
ICC
Use at an assay dependent concentration. |
靶标
-
相关性
Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr. -
细胞定位
Virion membrane -
数据库链接
- Entrez Gene: 2828293 Hepatitis B virus
- Entrez Gene: 944569 Hepatitis B virus
- SwissProt: P03138 Hepatitis B virus
- SwissProt: P03140 Hepatitis B virus
- SwissProt: P03141 Hepatitis B virus
- SwissProt: Q81157 Hepatitis B virus
- SwissProt: Q81158 Hepatitis B virus
- SwissProt: Q81159 Hepatitis B virus
see all -
别名
- HBsAg antibody
- HBV major surface antigen antibody
- HBV surface antigen antibody
see all
数据表及文件
-
SDS download
-
Datasheet download
文献 (3)
ab32914 被引用在 3 文献中.
- Wu Q et al. Presence of Intact Hepatitis B Virions in Exosomes. Cell Mol Gastroenterol Hepatol 15:237-259 (2023). PubMed: 36184032
- Deng Q et al. Hepatitis B virus as a gene delivery vector activating foreign antigenic T cell response that abrogates viral expression in mouse models. Hepatology 50:1380-91 (2009). PubMed: 19821533
- Deng Q et al. Identification and characterization of peptides that interact with hepatitis B virus via the putative receptor binding site. J Virol 81:4244-54 (2007). PubMed: 17192308