Anti-H4R抗体(ab97487)
Key features and details
- Rabbit polyclonal to H4R
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-H4R抗体
参阅全部 H4R 一抗 -
描述
兔多克隆抗体to H4R -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human H4R aa 1-100.
Database link: NP_067637 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 49.99% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97487于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 44 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 44 kDa. |
靶标
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功能
The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). -
组织特异性
Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 59340 Human
- Omim: 606792 Human
- SwissProt: Q9H3N8 Human
- Unigene: 287388 Human
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别名
- AXOR35 antibody
- BG26 antibody
- G protein coupled receptor 105 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab97487 被引用在 2 文献中.
- Clauzure M et al. Histamine H4 Receptor Agonism Induces Antitumor Effects in Human T-Cell Lymphoma. Int J Mol Sci 23:N/A (2022). PubMed: 35163302
- Speisky D et al. Histamine H4 Receptor Expression in Triple-negative Breast Cancer: An Exploratory Study. J Histochem Cytochem 70:311-322 (2022). PubMed: 35227109