Anti-H Cadherin抗体(ab36905)
Key features and details
- Rabbit polyclonal to H Cadherin
- Suitable for: IHC-P, WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-H Cadherin抗体
参阅全部 H Cadherin 一抗 -
描述
兔多克隆抗体to H Cadherin -
宿主
Rabbit -
特异性
This antibody is specific for H Cadherin. -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse -
免疫原
A 15 amino acid peptide from near the amino terminus of human H Cadherin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab36905于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P | (2) |
Use a concentration of 5 µg/ml.
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WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 78 kDa.
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说明 |
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IHC-P
Use a concentration of 5 µg/ml. |
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 78 kDa. |
靶标
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功能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. -
组织特异性
Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord. -
序列相似性
Contains 5 cadherin domains. -
发展阶段
Expressed at higher levels in adult brain than in developing brain. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 12554 Mouse
- SwissProt: Q9WTR5 Mouse
- Unigene: 334841 Mouse
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别名
- CAD13_HUMAN antibody
- Cadherin-13 antibody
- CDH13 antibody
see all
图片
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Lane 1 : Anti-H Cadherin antibody (ab36905) at 0.5 µg/ml
Lane 2 : Anti-H Cadherin antibody (ab36905) at 1 µg/ml
All lanes : 3T3 cell lysate.
Predicted band size: 78 kDa -
Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse brain tissue labeling H Cadherin with Anti-H Cadherin antibody (ab36905) at 5μg/ml.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab36905 被引用在 3 文献中.
- Sapio L et al. AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells. J Oncol 2020:7262479 (2020). PubMed: 32411241
- Wang Q et al. Down-regulation of adiponectin receptors in osteoarthritic chondrocytes. Cell Biochem Biophys 70:491-7 (2014). PubMed: 24888493
- Kuphal S et al. H-cadherin expression reduces invasion of malignant melanoma. Pigment Cell Melanoma Res 22:296-306 (2009). WB, ICC/IF ; Human . PubMed: 19368692