Anti-Gastrin抗体,prediluted (ab928)
Key features and details
- Rabbit polyclonal to Gastrin, prediluted
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Gastrin抗体,prediluted
参阅全部 Gastrin 一抗 -
描述
兔多克隆抗体to Gastrin,prediluted -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein corresponding to Gastrin conjugated to keyhole limpet haemocyanin.
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阳性对照
- IHC-P: Human stomach tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
存储溶液
pH: 7.3
Preservative: 0.05% Sodium azide
Inert stabilizer -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
骨髓瘤
unknown -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/50 - 1/100.
Incubate with primary antibody for 30 minutes at room temperature. |
说明 |
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IHC-P
1/50 - 1/100. Incubate with primary antibody for 30 minutes at room temperature. |
靶标
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功能
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. -
序列相似性
Belongs to the gastrin/cholecystokinin family. -
翻译后修饰
Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 2520 Human
- Omim: 137250 Human
- SwissProt: P01350 Human
- Unigene: 2681 Human
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别名
- Component II antibody
- G14 antibody
- G17 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (0)
ab928 尚未被引用在任何文献中。