Key features and details
- Rabbit polyclonal to GABA Transporter 3 / GAT 3
- Reacts with: Rat, Chicken
- Isotype: IgG
产品名称Anti-GABA Transporter 3 / GAT 3抗体
参阅全部 GABA Transporter 3 / GAT 3 一抗
描述兔多克隆抗体to GABA Transporter 3 / GAT 3
特异性This antibody reacts with a 74 kDa protein from CNS samples.
种属反应性与反应: Rat, Chicken
预测可用于: Mouse, Human
15 residue C-terminal synthetic peptide (Rat).
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Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液Constituent: Whole serum
Concentration information loading...
功能Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
组织特异性Widespread distribution in the brain.
序列相似性Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.
- Information by UniProt
- GABT3 antibody
- GAT-3 antibody
- GAT3 antibody
ab431 被引用在 8 文献中.
- Zhang W et al. Role of microRNA-155 in modifying neuroinflammation and ?-aminobutyric acid transporters in specific central regions after post-ischaemic seizures. J Cell Mol Med 23:5017-5024 (2019). PubMed: 31144434
- Barca-Mayo O et al. Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling. Nat Commun 8:14336 (2017). IF . PubMed: 28186121
- Zhang Y et al. Astrocytic Process Plasticity and IKKß/NF-?B in Central Control of Blood Glucose, Blood Pressure, and Body Weight. Cell Metab 25:1091-1102.e4 (2017). PubMed: 28467927
- Huo Q et al. Prefrontal Cortical GABAergic Dysfunction Contributes to Aberrant UP-State Duration in APP Knockout Mice. Cereb Cortex : (2016). PubMed: 27552836
- Dadsetan S et al. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. J Neuroinflammation 13:245 (2016). WB, IHC-P ; Rat . PubMed: 27623772
- Wu Z et al. Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzhiemer's disease model. Nat Commun 5:4159 (2014). IHC . PubMed: 24923909
- Aligny C et al. Ketamine alters cortical integration of GABAergic interneurons and induces long-term sex-dependent impairments in transgenic Gad67-GFP mice. Cell Death Dis 5:e1311 (2014). IHC (PFA fixed), WB ; Mouse . PubMed: 24991763
- Gosselin RD et al. Extracellular microvesicles from astrocytes contain functional glutamate transporters: regulation by protein kinase C and cell activation. Front Cell Neurosci 7:251 (2013). WB ; Rat . PubMed: 24368897