Key features and details
- Rabbit polyclonal to GABA Transporter 1 / GAT 1
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
产品名称Anti-GABA Transporter 1 / GAT 1抗体
参阅全部 GABA Transporter 1 / GAT 1 一抗
描述兔多克隆抗体to GABA Transporter 1 / GAT 1
特异性Reacts specifically with a 72 kDa protein.
经测试应用适用于: WBmore details
Synthetic peptide corresponding to Rat GABA Transporter 1/ GAT 1 (C terminal). 20 amino acids.
Database link: P23978
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液Constituent: Whole serum
Concentration information loading...
功能Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
序列相似性Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.
结构域The PDZ domain-binding motif is involved in the interaction with MPP5.
细胞定位Cell membrane. Membrane. Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons.
- Information by UniProt
- GABATHG antibody
- GABATR antibody
- GABT 1 antibody
All lanes : Anti-GABA Transporter 1 / GAT 1 antibody (ab426) at 1 µg/ml
Lane 1 : Rat Hippocampus Tissue Lysate
Lane 2 : Spinal Cord (Rat) Tissue Lysate
Lane 3 : Brain (Rat) Tissue Lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 67 kDa
Observed band size: 74 kDa why is the actual band size different from the predicted?
Exposure time: 30 seconds
GABA Transporter 1/ GAT 1 contains a number of potential glycosylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted.
ab426 被引用在 27 文献中.
- de Aquino PEA et al. A Proline Derivative-Enriched Fraction from Sideroxylon obtusifolium Protects the Hippocampus from Intracerebroventricular Pilocarpine-Induced Injury Associated with Status Epilepticus in Mice. Int J Mol Sci 21:N/A (2020). PubMed: 32545390
- Østergaard FG et al. Classification of a-synuclein-induced changes in the AAV a-synuclein rat model of Parkinson's disease using electrophysiological measurements of visual processing. Sci Rep 10:11869 (2020). PubMed: 32681050
- Guimarães-Souza EM et al. Retinal alterations in a pre-clinical model of an autism spectrum disorder. Mol Autism 10:19 (2019). PubMed: 31011411
- Zhang W et al. Role of microRNA-155 in modifying neuroinflammation and ?-aminobutyric acid transporters in specific central regions after post-ischaemic seizures. J Cell Mol Med 23:5017-5024 (2019). PubMed: 31144434
- Leonetti A et al. Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase. Amino Acids N/A:N/A (2019). PubMed: 31197571