Key features and details
- Rabbit polyclonal to FAT4
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
经测试应用适用于: WB, ICC/IFmore details
Synthetic peptide conjugated to KLH corresponding to a region within Human FAT4 (SwissProt Q6V0I7).
- recombinant FAT4 protein
存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.05% Sodium azide
Constituents: 74% Tris buffered saline, 25% Glycerol, 0.5% BSA
Concentration information loading...
纯度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab130076 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 543 kDa).|
|ICC/IF||1/50 - 1/100.|
功能May function in the regulation of planar cell polarity (By similarity). Cadherins are cell-cell interaction molecules.
组织特异性Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer.
序列相似性Contains 34 cadherin domains.
Contains 6 EGF-like domains.
Contains 2 laminin G-like domains.
细胞定位Membrane. In the kidney, localizes to primary cilia.
- Information by UniProt
- Cadherin family member 14 antibody
- Cadherin related family member 11 antibody
- CDHF14 antibody
ab130076 被引用在 3 文献中.
- Che X et al. FAT4-USP51 complex regulates the proliferation and invasion of endometrial cancer via Hippo pathway. Am J Transl Res 11:2784-2800 (2019). PubMed: 31217854
- Li SY et al. Down-regulated long non-coding RNA RNAZFHX4-AS1 suppresses invasion and migration of breast cancer cells via FAT4-dependent Hippo signaling pathway. Cancer Gene Ther N/A:N/A (2018). PubMed: 30546116
- Ma L et al. Fat4 suppression induces Yap translocation accounting for the promoted proliferation and migration of gastric cancer cells. Cancer Biol Ther 17:36-47 (2016). WB ; Human . PubMed: 26575609