PE Anti-F4/80抗体[CI:A3-1] (ab105156)
Key features and details
- PE Rat monoclonal [CI:A3-1] to F4/80
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2b
Related conjugates and formulations
概述
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产品名称
PE Anti-F4/80抗体[CI:A3-1]
参阅全部 F4/80 一抗 -
描述
PE大鼠单克隆抗体[CI:A3-1] to F4/80 -
宿主
Rat -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
ab105156 recognises the murine F4/80 antigen. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse F4/80. Thioglycollate stimulated peritoneal cavity macrophages from C57/BL mice.
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阳性对照
- Mouse J774 cells
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常规说明
Clone CI:A3-1 has been reported to modulate cytokine levels released in response to Listeria monocytogenes.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, 5% Sucrose, PBS -
Concentration information loading...
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纯度
Protein A purified -
Primary antibody说明
Clone CI:A3-1 has been reported to modulate cytokine levels released in response to Listeria monocytogenes. -
克隆
单克隆 -
克隆编号
CI:A3-1 -
骨髓瘤
NS1 -
同种型
IgG2b -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105156于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 10µl for 106 cells.
in 100 µl. ab136585 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt
Use 10µl for 106 cells. in 100 µl. ab136585 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. -
组织特异性
Expression is restricted to eosinophils. -
序列相似性
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Contains 6 EGF-like domains.
Contains 1 GPS domain. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 13733 Mouse
- SwissProt: Q61549 Mouse
- Unigene: 2254 Mouse
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别名
- ADGRE1 antibody
- Adhesion G protein coupled receptor E1 antibody
- Adhesion G protein-coupled receptor E1 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab105156 被引用在 7 文献中.
- Babazadeh S et al. Macrophage polarization by MSC-derived CXCL12 determines tumor growth. Cell Mol Biol Lett 26:30 (2021). PubMed: 34174813
- Liu X et al. Fruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization. Cell Death Dis 11:1016 (2020). PubMed: 33247124
- Shimizu Y et al. A simple culture method for liver and intestinal tissue-resident macrophages from neonatal mice. In Vitro Cell Dev Biol Anim 55:436-444 (2019). PubMed: 31119642
- Li H et al. Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat. Nat Commun 9:272 (2018). PubMed: 29348470
- Huang Z et al. The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity. Cell Metab 26:493-508.e4 (2017). PubMed: 28844880
- Rokade S et al. Surfactant protein D regulates murine testicular immune milieu and sperm functions. Am J Reprod Immunol 77:N/A (2017). PubMed: 28054406
- Neng L et al. Isolation and culture of endothelial cells, pericytes and perivascular resident macrophage-like melanocytes from the young mouse ear. Nat Protoc 8:709-20 (2013). PubMed: 23493068