Anti-DEPDC5抗体(ab185565)
Key features and details
- Rabbit polyclonal to DEPDC5
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-DEPDC5抗体
参阅全部 DEPDC5 一抗 -
描述
兔多克隆抗体to DEPDC5 -
宿主
Rabbit -
经测试应用
适用于: ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Recombinant fragment corresponding to Human DEPDC5 aa 450-550.
Database link: O75140 -
阳性对照
- Human stomach tissue.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab185565于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
|
说明 |
---|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
靶标
-
序列相似性
Belongs to the IML1 family.
Contains 1 DEP domain. - Information by UniProt
-
数据库链接
- Entrez Gene: 9681 Human
- Entrez Gene: 277854 Mouse
- Omim: 614191 Human
- SwissProt: O75140 Human
- SwissProt: P61460 Mouse
- Unigene: 435022 Human
-
别名
- DEP domain containing 5 antibody
- DEP domain-containing protein 5 antibody
- DEP.5 antibody
see all
图片
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (4)
ab185565 被引用在 4 文献中.
- Bacq A et al. Cardiac Investigations in Sudden Unexpected Death in DEPDC5-Related Epilepsy. Ann Neurol 91:101-116 (2022). PubMed: 34693554
- Figlia G et al. Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition. Nat Cell Biol 24:1407-1421 (2022). PubMed: 36097071
- De Fusco A et al. Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis. Neurobiol Dis 139:104822 (2020). PubMed: 32113911
- Graber TG et al. Skeletal muscle-specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration. J Biol Chem 294:4091-4102 (2019). PubMed: 30635399