Anti-DECTIN 2抗体[IMG3D1] (ab107572)


  • 产品名称
    Anti-DECTIN 2抗体[IMG3D1]
    参阅全部 DECTIN 2 一抗
  • 描述
    小鼠单克隆抗体[IMG3D1] to DECTIN 2
  • 宿主
  • 经测试应用
    适用于: WB, IHC-P, Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Rat, Human, Chimpanzee, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to amino acids 75-125 of Human DECTIN 2 (Q6EIG7).

  • 阳性对照
    • Human, mouse and rat heart lysate, human Ramos cell lysate, human PBMCs and human spleen tissue.


  • 形式
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.05% Sodium Azide
    Constituents: 0.05% BSA, PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
  • 克隆编号
  • 同种型
  • 轻链类型
  • 研究领域


Our Abpromise guarantee covers the use of ab107572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2 - 5 µg/ml. Predicted molecular weight: 24 kDa.
IHC-P Use a concentration of 5 µg/ml.
Flow Cyt Use at an assay dependent concentration.

Use 0.5 ug/5x105 cells




ab18392 - Mouse monoclonal IgG3, is suitable for use as an isotype control with this antibody.



  • 功能
    Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.
  • 组织特异性
    Expressed in lung, spleen, lymph node, leukocytes, bone marrow, tonsils and dendritic cells. Strongly expressed in purified monocytes and weakly in B-cells. In peripheral blood cells, preferentially expressed in plasmacytoids rather than myeloids.
  • 序列相似性
    Contains 1 C-type lectin domain.
  • 结构域
    A short stretch of the intracellular domain (AA 8-14) proximal to the transmembrane domain is required for association with Fc receptor gamma chain.
  • 细胞定位
  • Information by UniProt
  • 数据库链接
  • 别名
    • C type lectin domain family 6 member A antibody
    • C type lectin superfamily member 10 antibody
    • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10 antibody
    • C-type lectin domain family 6 member A antibody
    • C-type lectin superfamily member 10 antibody
    • CLC6A_HUMAN antibody
    • CLEC4N antibody
    • CLEC4N, mouse, homolog of antibody
    • Clec6a antibody
    • CLECSF10 antibody
    • DC associated C type lectin 2 antibody
    • DC-associated C-type lectin 2 antibody
    • Dectin-2 antibody
    • Dectin2 antibody
    • Dendritic cell associated lectin 2 antibody
    • Dendritic cell-associated C-type lectin 2 antibody
    see all


  • All lanes : Anti-DECTIN 2 antibody [IMG3D1] (ab107572) at 2 µg/ml

    Lane 1 : Human heart lysate
    Lane 2 : Human heart lysate with immunizing peptide
    Lane 3 : Mouse heart lysate
    Lane 4 : Rat heart lysate
    Lane 5 : Human Ramos cell lysate

    All lanes : goat anti-mouse Ig HRP

    Predicted band size: 24 kDa

  • Cell surface flow cytometric analysis of DECTIN 2 expression by 5x10^5 human PBMCs using 0.5 µg of ab107572 in red and 0.5 µg of isotype control in green.
  • Immunohistochemical analysis of DECTIN 2 in formalin-fixed, paraffin-embedded human spleen tissue using ab107572 at 5 µg/ml.


ab107572 has not yet been referenced specifically in any publications.


Thank you for your patience. I am pleased to hear that enzymatic antigen retrieval seemed to help. After discussing this with a colleague I also have the following suggestions: - The blocking conditions are quite stringent therefore it is worth...

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Thank you for your patience. I think is makes sense to investigate the problems with IHC-P to see whether some protocol modifications will get the product working successfully, as we don’t know whether it is suitable for GMA embedded tissues. Would...

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Thank you for calling us today. I am sorry to hear you have been experiencing problems with this product. We have not received any other complaints about this product therefore there may be a problem with the vial received. I would be happy to offer ...

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