Anti-DcR2抗体(ab2019)
Key features and details
- Rabbit polyclonal to DcR2
- Suitable for: ICC, WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-DcR2抗体
参阅全部 DcR2 一抗 -
描述
兔多克隆抗体to DcR2 -
宿主
Rabbit -
特异性
Human, Mouse, Rat -
经测试应用
适用于: ICC, WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human DcR2 aa 249-263.
Sequence:GGPERVHRVLFRRRS
(Peptide available asab8379) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC |
Use a concentration of 10 µg/ml.
|
|
| WB |
1/1000 - 1/2000.
|
| 说明 |
|---|
|
ICC
Use a concentration of 10 µg/ml. |
|
WB
1/1000 - 1/2000. |
靶标
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功能
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. -
组织特异性
Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart. -
序列相似性
Contains 1 death domain.
Contains 3 TNFR-Cys repeats. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 8793 Human
- Omim: 603614 Human
- SwissProt: Q9UBN6 Human
- Unigene: 213467 Human
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别名
- CD 264 antibody
- CD264 antibody
- DcR 2 antibody
see all
图片
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Western blot - Anti-DcR2 antibody (ab2019)Anti-DcR2 antibody (ab2019) at 1/1000 dilution + HeLa whole cell lysate
Observed band size: 35 kDa why is the actual band size different from the predicted? -
Immunocytochemistry - Anti-DcR2 antibody (ab2019)ab2019 at 10µg/ml staining DcR2 in human Hela cells by Immunocytochemistry.
实验方案
数据表及文件
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Datasheet download
文献 (11)
ab2019 被引用在 11 文献中.
- Jiao-Yan Y et al. Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression. Phytomedicine 84:153505 (2021). PubMed: 33626426
- Wang Z et al. Enhancing the antitumor activity of an engineered TRAIL-coated oncolytic adenovirus for treating acute myeloid leukemia. Signal Transduct Target Ther 5:40 (2020). PubMed: 32327638
- Brunetti G et al. High expression of TRAIL by osteoblastic differentiated dental pulp stem cells affects myeloma cell viability. Oncol Rep 39:2031-2039 (2018). PubMed: 29484421
- You C et al. ß-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors. Int J Oncol 53:2258-2268 (2018). PubMed: 30132512
- Chung SI et al. Comparison of liver oncogenic potential among human RAS isoforms. Oncotarget 7:7354-66 (2016). PubMed: 26799184
