Key features and details
- Goat polyclonal to DcR1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
参阅全部 DcR1 一抗
特异性<0.2% cross-reactivity to TRAIL R2 peptide of the same region. Not likely to bind TRAIL R1 due to low sequence homology in this region. May bind TRAIL R4. May cross react to mouse TRAIL R3 as antibody binds to a similar size protein from mouse spleen on Westerns.
经测试应用适用于: WBmore details
- Human embryonic kidney cell line-293 or human T-cell line Jurkatt.
常规说明TRAIL R3 = "TNF Related Apoptosis Inducing Ligand Receptor 3"
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液Preservative: 0.1% Sodium azide
Constituent: 0.1% BSA
Concentration information loading...
纯度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab1674 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
相关性DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
细胞定位Cell Membrane and Cytoplasmic
- Antagonist decoy receptor for TRAIL/Apo 2L antibody
- CD263 antibody
- Cytotoxic TRAIL receptor 3 antibody
ab1674 recognizes a 66kDa band of expected size in Lane 1 containing TRAIL-3R-Fc protein and showed minimal or no crossreactivity to TRAIL-2R-Fc protein in Lane 2. ab1674 recognizes a 66kDa band of expected size in Lane 1 containing TRAIL-3R-Fc protein and showed minimal or no crossreactivity to TRAIL-2R-Fc protein in Lane 2.