重组Anti-Cytokeratin 8抗体[SP102],prediluted (ab228149)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [SP102] to Cytokeratin 8, prediluted
- Suitable for: IHC-P
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-Cytokeratin 8抗体[SP102],prediluted
参阅全部 Cytokeratin 8 一抗 -
描述
兔单克隆抗体[SP102] to Cytokeratin 8,prediluted -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Pig -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- IHC-P: Human breast ductal carcinoma, breast, lung squamous cell carcinoma, placenta, thyroid, bladder, bladder transitional cell carcinoma, stomach, stomach adenocarcinoma, prostate, prostate adenocarcinoma and lung tissue.
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常规说明
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
存储溶液
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: Tris buffered saline, 1% BSA -
Concentration information loading...
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纯度
Protein A/G purified -
纯化说明
Purified from TCS by protein A/G. -
克隆
单克隆 -
克隆编号
SP102 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab228149于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/1. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Ready to use. Primary antibody incubation for 30 minutes at room temperature. |
说明 |
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IHC-P
1/1. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Ready to use. Primary antibody incubation for 30 minutes at room temperature. |
靶标
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功能
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. -
组织特异性
Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. -
疾病相关
Cirrhosis -
序列相似性
Belongs to the intermediate filament family. -
翻译后修饰
Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner. -
细胞定位
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 281269 Cow
- Entrez Gene: 3856 Human
- Entrez Gene: 16691 Mouse
- Entrez Gene: 100152077 Pig
- Entrez Gene: 25626 Rat
- Omim: 148060 Human
- SwissProt: P05786 Cow
- SwissProt: P05787 Human
see all -
别名
- CARD2 antibody
- CK 8 antibody
- CK-8 antibody
see all
图片
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Formalin-fixed, paraffin-embedded human lung tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human breast ductal carcinoma tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human breast tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human lung squamous cell carcinoma tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human placenta tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human thyroid tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human bladder tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human bladder transitional cell carcinoma tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human stomach tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human stomach adenocarcinoma tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human prostate tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human prostate adenocarcinoma tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human breast ductal carcinoma tissue stained for Cytokeratin 8 using ab228149 in immunohistochemical analysis.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab228149 尚未被引用在任何文献中。