Key features and details
- Mouse monoclonal [35bH11] to Cytokeratin 8
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgM
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
参阅全部 Cytokeratin 8 一抗
描述小鼠单克隆抗体[35bH11] to Cytokeratin 8
经测试应用适用于: IHC-Pmore details
Tissue, cells or virus corresponding to Cytokeratin 8. Cytoskeletal extract of human hepatocellular carcinoma cell line, Hep3B
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.05% Sodium azide
Constituents: Tissue culture supernatant, 1% BSA
Concentration information loading...
纯度Tissue culture supernatant
The Abpromise guarantee
1/25 - 1/50.
1/25 - 1/50.
功能Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
组织特异性Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
序列相似性Belongs to the intermediate filament family.
翻译后修饰Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
细胞定位Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
- Information by UniProt
- CARD2 antibody
- CK 8 antibody
- CK-8 antibody
ab758 被引用在 1 文献中.
- Berger R et al. Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. Cancer Res 64:8867-75 (2004). PubMed: 15604246