概述

  • 产品名称
    Anti-Cytokeratin 13抗体
    参阅全部 Cytokeratin 13 一抗
  • 描述
    山羊多克隆抗体to Cytokeratin 13
  • 宿主
    Goat
  • 特异性
    ab79279 is expected to recognize the reported isoform a (NP_705694.2) only.
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-TSNASGRRTSDVRRP

    , corresponding to C terminal amino acids 444-458 of Human Cytokeratin 13 (NP_705694.2)

  • 阳性对照
    • Human Lung, Skeletal Muscle and Skin lysates.

性能

应用

Our Abpromise guarantee covers the use of ab79279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明
    Peptide ELISA: Antibody detection limit dilution 1/128000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 50 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 组织特异性
      Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
    • 疾病相关
      Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
    • 序列相似性
      Belongs to the intermediate filament family.
    • 翻译后修饰
      O-glycosylated; glycans consist of single N-acetylglucosamine residues.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 47 kDa cytokeratin antibody
      • CK-13 antibody
      • CK13 antibody
      • Cytokeratin 13 antibody
      • Cytokeratin-13 antibody
      • K13 antibody
      • K1C13_HUMAN antibody
      • Ka13 antibody
      • Keratin 13 antibody
      • Keratin antibody
      • keratin type I cytoskeletal 13 antibody
      • Keratin-13 antibody
      • Krt-1.13 antibody
      • Krt1-13 antibody
      • KRT13 antibody
      • MGC161462 antibody
      • MGC3781 antibody
      • type I cytoskeletal 13 antibody
      • Type I keratin Ka13 antibody
      • WSN2 antibody
      see all

    图片

    • Anti-Cytokeratin 13 antibody (ab79279) at 0.1 µg/ml + Human Lung lysate (in RIPA buffer) at 35 µg

      Predicted band size: 50 kDa
      Observed band size: 55 kDa
      why is the actual band size different from the predicted?



      The observed molecular weight corresponds to earlier findings in literature with different antibodies (Sajjan, Microbiology. 2003 Apr;149(Pt 4):961-71.; PMID: 12686638)

    实验方案

    文献

    ab79279 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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