Key features and details
- Rabbit polyclonal to CYP8B1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
Concentration information loading...
纯度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab129845 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 58 kDa.|
|IHC-P||1/50 - 1/100.|
功能Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
序列相似性Belongs to the cytochrome P450 family.
细胞定位Endoplasmic reticulum membrane. Microsome membrane.
- Information by UniProt
- 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase antibody
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase antibody
- CP8B antibody
All lanes : Anti-CYP8B1 antibody (ab129845) at 1/500 dilution
Lane 1 : 293 cell extract
Lane 2 : 293 cell extract with synthesized peptide
Predicted band size: 58 kDa
ab129845, at a dilution of 1/50, staining CYP8B1 in paraffin-embedded Human liver carcinoma tissue by Immunohistochemistry. The picture on the right was treated with synthesized peptide.