Key features and details
- Rabbit polyclonal to CYFIP2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
经测试应用适用于: WB, IHC-Pmore details
预测可用于: Mouse, Rat
Recombinant fragment, corresponding to a region within amino acids 346-610 of Human CYFIP2 (UniProt ID: Q96F07 isoform 2; NP_055191).
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
纯度Immunogen affinity purified
相关性CYFIP2 is involved in T cell adhesion and p53 dependent induction of apoptosis. It does not bind RNA but is up regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis. There are 2 isoforms produced by alternative splicing.
细胞定位Cytoplasm perinuclear region. Cell junction, synapse, synaptosome. Treatment with leptomycin-B triggers translocation to the nucleus.
- CYFP2 antibody
- cytoplasmic FMR1 interacting protein 2 antibody
- KIAA1168 antibody
ab95969 被引用在 8 文献中.
- Petrick HL et al. Adipose Tissue Inflammation Is Directly Linked to Obesity-Induced Insulin Resistance, while Gut Dysbiosis and Mitochondrial Dysfunction Are Not Required. Function (Oxf) 1:zqaa013 (2020). WB . PubMed: 34278304
- Zhang Y et al. Enhanced Prefrontal Neuronal Activity and Social Dominance Behavior in Postnatal Forebrain Excitatory Neuron-Specific Cyfip2 Knock-Out Mice. Front Mol Neurosci 13:574947 (2020). PubMed: 33192297
- Zhang Y et al. Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus. Anim Cells Syst (Seoul) 23:380-383 (2019). PubMed: 31853374
- Marsden KC et al. A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold. Cell Rep 23:878-887 (2018). IHC ; Zebrafish . PubMed: 29669291
- Han K et al. Fragile X-like behaviors and abnormal cortical dendritic spines in cytoplasmic FMR1-interacting protein 2-mutant mice. Hum Mol Genet 24:1813-23 (2015). PubMed: 25432536
- Taha MS et al. Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin. PLoS One 9:e91465 (2014). ICC/IF ; Human . PubMed: 24658146
- Han K et al. SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature 503:72-7 (2013). Mouse . PubMed: 24153177
- Mongroo PS et al. IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2. Cancer Res 71:2172-82 (2011). WB ; Human . PubMed: 21252116