Anti-Cyclin A1抗体(ab172317)
Key features and details
- Mouse polyclonal to Cyclin A1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Cyclin A1抗体
参阅全部 Cyclin A1 一抗 -
描述
小鼠多克隆抗体to Cyclin A1 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rat -
免疫原
Recombinant full length protein within Human Cyclin A1 aa 1 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. (ABM85414.1).
Database link: P78396-2 -
阳性对照
- Cyclin A1 transfected 293T cell line lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab172317于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa.
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说明 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. |
靶标
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功能
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. -
组织特异性
Very high levels in testis and very low levels in brain. Also found in myeloid Leukemia cell lines. -
序列相似性
Belongs to the cyclin family. Cyclin AB subfamily. -
发展阶段
Expression increases in early G1 phase and reaches highest levels during the S and G2/M phases. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 8900 Human
- Entrez Gene: 295052 Rat
- Omim: 604036 Human
- SwissProt: P78396 Human
- SwissProt: Q6AY13 Rat
- Unigene: 417050 Human
- Unigene: 102823 Rat
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别名
- CCN A1 antibody
- CCNA 1 antibody
- Ccna1 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (2)
ab172317 被引用在 2 文献中.
- Ji W et al. c-myc regulates the sensitivity of breast cancer cells to palbociclib via c-myc/miR-29b-3p/CDK6 axis. Cell Death Dis 11:760 (2020). PubMed: 32934206
- Yang L et al. Transcriptional co-activator with PDZ-binding motif overexpression promotes cell proliferation and transcriptional co-activator with PDZ-binding motif deficiency induces cell cycle arrest in neuroblastoma. Oncol Lett 13:4295-4301 (2017). WB . PubMed: 28599430