为了使您在Abcam官网的浏览体验更顺畅,请使用最新版本的浏览器比如 Google Chrome

Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online
致电 +86 21 2070 0500 或 联系我们

  • 我的账户
  • 退出
登录 或 注册

欢迎光临

登录 或

您还没有帐户?

注册
我的购物篮
快速订购
Abcam homepage

  • 研究用途的产品
    按产品类型
    一抗
    二抗
    免疫测定试剂盒与试剂
    细胞与组织成像工具
    细胞与生化测定
    蛋白质与肽
    按产品类型
    蛋白质组学工具
    激动剂、活化剂、拮抗剂与抑制剂
    细胞株和裂解液
    多重miRNA检测
    多因子分析试剂盒
    按研究领域
    癌症
    心血管
    细胞生物学
    表观遗传学
    代谢
    发育生物学
    按研究领域
    免疫学
    微生物学
    神经科学
    信号转导
    干细胞
  • 定制化产品 & 合作关系
    定制化产品 & 合作关系

    定制化产品和商务合作加速您的诊断和治疗项目

    定制化产品

    与我们成为伙伴

  • 技术支持
    支持中心

    获取研究建议和支持

    查看支持中心

    Protocols

    一步一步完成您的实验

    查看Protocols

  • 活动通知
    • 会议年历
    • 肿瘤研究
    • 心血管研究
    • 染色质及细胞核信号转导研究
    • 免疫学
    • 神经生物学
    • 干细胞研究
    • 商品展览
    • 实验技术视频
    查看最新活动

    活动说明、摘要提交、演讲者、注册方式及更多信息

    查看全球活动安排

  • 通路
    细胞信号转导通路

    查看所有通路

    查看交叉通路

在新冠疫情期间支持我们的客户和员工–了解更多

Microbiology Interspecies Interaction Host Virus Interaction

Anti-CXCR6抗体(ab8023)

  • Datasheet
Reviews (1) Submit a question References (9)

Product price, shipping and contact information

Currently unavailable

抱歉,我们目前无法显示此内容。

请联系我们以完成下单,或者之后再尝试访问。

 

正在加载规格和价格。。。

 

送货和订单信息

运输费用

Promotion Information

Abpromise

产品质量保证,客户专家支持,

点击获取更多

Immunofluorescence - Anti-CXCR6 antibody (ab8023)
  • Western blot - Anti-CXCR6 antibody (ab8023)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCR6 antibody (ab8023)

Key features and details

  • Rabbit polyclonal to CXCR6
  • Suitable for: IHC-P, WB
  • Reacts with: Human
  • Isotype: IgG

你可能会感兴趣

一抗
Product image
Anti-F4/80 antibody [SP115] (ab111101)
一抗
Product image
Anti-CD8 alpha antibody [C8/144B] (ab17147)
一抗
Product image
Anti-Fas antibody [EPR5700] - BSA and Azide free (ab178076)

查看更多相关产品

概述

  • 产品名称

    Anti-CXCR6抗体
    参阅全部 CXCR6 一抗
  • 描述

    兔多克隆抗体to CXCR6
  • 宿主

    Rabbit
  • 经测试应用

    适用于: IHC-P, WBmore details
  • 种属反应性

    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids 11-25 of Human Bonzo.

  • 阳性对照

    • Human spleen tissue lysate
  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid
  • 存放说明

    Shipped at 4°C. Store at +4°C.
  • 存储溶液

    pH: 7.2
    Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度

    Affinity purified
  • 克隆

    多克隆
  • 同种型

    IgG
  • 研究领域

    • Microbiology
    • Interspecies Interaction
    • Host Virus Interaction
    • Immunology
    • Immune System Diseases
    • Antiviral Signaling
    • HIV-related

相关产品

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Conjugation kits

    • PE / R-Phycoerythrin Conjugation Kit - Lightning-Link® (ab102918)
    • APC Conjugation Kit - Lightning-Link® (ab201807)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab8023于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
IHC-P
Use a concentration of 2.5 - 20 µg/ml.
WB
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 44 kDa.
IF
Use a concentration of 20 µg/ml.
说明
IHC-P
Use a concentration of 2.5 - 20 µg/ml.
WB
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 44 kDa.
IF
Use a concentration of 20 µg/ml.

靶标

  • 功能

    Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
  • 组织特异性

    Expressed in lymphoid tissues and activated T cells.
  • 序列相似性

    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位

    Cell membrane.
  • Target information above from: UniProt accession O00574 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • 数据库链接

    • Entrez Gene: 10663 Human
    • Omim: 605163 Human
    • SwissProt: O00574 Human
    • Unigene: 34526 Human
    • 别名

      • bonzo antibody
      • C X C chemokine receptor type 6 antibody
      • C-X-C chemokine receptor type 6 antibody
      • CD 186 antibody
      • CD186 antibody
      • CD186 antigen antibody
      • CDw186 antibody
      • Chemokine (C X C motif) receptor 6 antibody
      • Chemokine C X C motif receptor 6 antibody
      • Chemokine CXC motif receptor 6 antibody
      • Chemokine receptor 6 antibody
      • CXC chemokine receptor type 6 antibody
      • CXC R6 antibody
      • CXC-R6 antibody
      • CXCR 6 antibody
      • CXCR-6 antibody
      • CXCR6 antibody
      • CXCR6_HUMAN antibody
      • G protein coupled receptor antibody
      • G protein coupled receptor bonzo antibody
      • G protein coupled receptor STRL 33 antibody
      • G protein coupled receptor STRL33 antibody
      • G protein coupled receptor TYMSTR antibody
      • G-protein coupled receptor bonzo antibody
      • G-protein coupled receptor STRL33 antibody
      • STRL 33 antibody
      • STRL33 antibody
      • TYMSTR antibody
      see all

    图片

    • Immunofluorescence - Anti-CXCR6 antibody (ab8023)
      Immunofluorescence - Anti-CXCR6 antibody (ab8023)

      Immunofluorescence of human spleen tissue labeling CXCR6 (Green) using ab8023 at 20 µg/ml. DAPI staining (Blue).

    • Western blot - Anti-CXCR6 antibody (ab8023)
      Western blot - Anti-CXCR6 antibody (ab8023)
      All lanes : Anti-CXCR6 antibody (ab8023) at 1/500 dilution

      Lane 1 : human spleen tissue lysate with absence of peptide
      Lane 2 : human spleen tissue lysate with presence of peptide

      Predicted band size: 44 kDa
      Observed band size: 44 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCR6 antibody (ab8023)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCR6 antibody (ab8023)

      ab8023 at 20µg/ml staining CXCR6 in human spleen cells by IHC

    实验方案

    • Flow cytometry protocols
    • Immunohistochemistry protocols
    • Immunocytochemistry & immunofluorescence protocols
    • Western blot protocols

    Click here to view the general protocols

    数据表及文件

    • Datasheet download

      Download

    文献 (9)

    发表研究结果有使用 ab8023?请让我们知道,以便我们可以引用本数据表中的参考文章。

    ab8023 被引用在 9 文献中.

    • Zhang J  et al. Determination of Potential Therapeutic Targets and Prognostic Markers of Ovarian Cancer by Bioinformatics Analysis. Biomed Res Int 2021:8883800 (2021). PubMed: 33829065
    • Tu GW  et al. CXCL16/CXCR6 is involved in LPS-induced acute lung injury via P38 signalling. J Cell Mol Med 23:5380-5389 (2019). PubMed: 31199046
    • Li S  et al. Oxidative stress drives CD8+ T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes. J Allergy Clin Immunol 140:177-189.e9 (2017). PubMed: 27826097
    • Ke C  et al. Association between CXCL16/CXCR6 expression and the clinicopathological features of patients with non-small cell lung cancer. Oncol Lett 13:4661-4668 (2017). PubMed: 28599467
    • Cui W  et al. miR-361-5p inhibits hepatocellular carcinoma cell proliferation and invasion by targeting VEGFA. Biochem Biophys Res Commun 479:901-906 (2016). PubMed: 27641667
    • Sun JJ  et al. MicroRNA-361-5p Inhibits Cancer Cell Growth by Targeting CXCR6 in Hepatocellular Carcinoma. Cell Physiol Biochem 38:777-85 (2016). PubMed: 26872014
    • Sellerio AL  et al. Overshoot during phenotypic switching of cancer cell populations. Sci Rep 5:15464 (2015). PubMed: 26494317
    • Toiyama Y  et al. Evaluation of CXCL10 as a novel serum marker for predicting liver metastasis and prognosis in colorectal cancer. Int J Oncol 40:560-6 (2012). PubMed: 22038159
    • Manabe S  et al. Expression and localization of CXCL16 and CXCR6 in ovarian endometriotic tissues. Arch Gynecol Obstet 284:1567-72 (2011). IHC-P ; Human . PubMed: 21773780

    客户评价及客户问答

    Show All 评价 Q&A
    提交评价 提交问题

    Flow Cytometry abreview for Anti-Bonzo antibody

    Good
    Abreviews
    Abreviews
    abreview image
    Application
    Flow Cytometry
    Sample
    Human Cell (human cancer cell line MCF-7)
    Specification
    human cancer cell line MCF-7
    Permeabilization
    No
    Gating Strategy
    LIVE
    Read More

    Abcam user community

    Verified customer

    提交于 May 28 2010

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    通过邮件收到学术资源和促销信息 注册
    研究类别(A-Z)
    • 肿瘤研究
    • 心血管研究
    • 细胞生物学
    • 发育生物学
    • 染色质及细胞核信号转导研究
    • 免疫学
    • 代谢
    • 微生物学
    • 神经生物学
    • 信号转导研究
    • 干细胞研究
    产品种类(A-Z)
    • 一抗
    • 二抗
    • 生化试剂
    • 亚类对照
    • 流式细胞仪多色选择器
    • 试剂盒
    • 内参对照
    • 细胞裂解液
    • 多肽
    • 蛋白酶
    • 组织切片
    • 蛋白标签及细胞标记物
    • 相关试剂及工具
    帮助与支持
    • 技术支持
    • 技术FAQ
    • 实验步骤与建议
    • 购买FAQ
    • RabMAb 产品
    • 培训课程
    • 按靶标浏览
    企业
    • 企业资讯
    • 投资者关系
    • 公司新闻
    • 招贤纳士
    • 关于我们
    活动通知
    • 商品展览
    • 会议
    全球网站
    • abcam.com
    • abcam.co.jp
    QR code for Weechat

    微信扫码 关注我们

    沪ICP备14046373号-1

    沪公网安备 31011502007413号

    • 销售条款
    • 网站使用条款
    • Cookie政策
    • 隐私权政策
    • 法律
    © 1998-2022 艾博抗(上海)贸易有限公司版权所有