存放说明Shipped at 4°C. Store at +4°C.
存储溶液Preservative: 0.02% Sodium azide
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Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab8021 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||Use at an assay dependent concentration.|
|Flow Cyt||Use at an assay dependent concentration.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
|WB||Use at an assay dependent concentration. Can be blocked with CX3CR1 peptide (ab8125).|
|IHC-P||Use at an assay dependent concentration.|
功能Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
组织特异性Expressed in lymphoid and neural tissues.
序列相似性Belongs to the G-protein coupled receptor 1 family.
- Information by UniProt
- Beta chemokine receptor-like 1 antibody
- C X3 C CKR 1 antibody
- C-X3-C CKR-1 antibody
Immunofluorescence of CX3CR1 in mouse heart tissue with ab8021 at 20 ug/ml. Green: ab8021 Blue: DAPI staining
Mouse heart tissue stained for CX3CR1 using ab8021 at 2 µg/ml in immunohistochemical analysis.
All lanes : Anti-CX3CR1 antibody (ab8021) at 1 µg/ml
Lane 1 : Human spleen lysate with absence of blocking peptide.
Lane 2 : Human spleen lysate with presence of blocking peptide.
Observed band size: 50 kDa why is the actual band size different from the predicted?
Immunohistochemical staining (paraffin embedded) of human heart tissue using anti-CX3CR1 at 2 µg/ml.
Immunofluorescence of CX3CR1 in Human Heart cells using ab8021 at 10 ug/ml.
Flow cytometry analysis of THP-1 cells using CX3CR1 antibody (ab8021) at 0.1 ug/ml.
Green: Isotype control
Red: CX3CR1 antibody (ab8021)
This product has been referenced in:
- Wang J et al. Ischemia-induced Neuronal Cell Death Is Mediated by Chemokine Receptor CX3CR1. Sci Rep 8:556 (2018). Read more (PubMed: 29323156) »
- Balzano T et al. The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons. Sci Rep 8:3004 (2018). Read more (PubMed: 29445232) »