Anti-CTGF抗体(ab6992)
Key features and details
- Rabbit polyclonal to CTGF
- Suitable for: IHC-P, ICC/IF, IHC-FoFr, WB, IHC-Fr, IP
- Reacts with: Mouse, Rat, Sheep, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-CTGF抗体
参阅全部 CTGF 一抗 -
描述
兔多克隆抗体to CTGF -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IF, IHC-FoFr, WB, IHC-Fr, IPmore details -
种属反应性
与反应: Mouse, Rat, Sheep, Human
预测可用于: Cow
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免疫原
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阳性对照
- human hippocampal protein extracts (see Ueberham et al paper).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (10) |
Use at an assay dependent concentration.
|
| ICC/IF | (4) |
Use at an assay dependent concentration.
|
| IHC-FoFr | (1) |
Use at an assay dependent concentration.
|
| WB | (10) |
Use at an assay dependent concentration. Predicted molecular weight: 38 kDa.
Block membrane in 4% BSA in Tris-buffered saline containing 0.05% Tween 20 (TBST). See Fu M et al. |
| IHC-Fr | (2) |
Use at an assay dependent concentration.
See Ueberham et al. |
| IP |
Use at an assay dependent concentration. PubMed: 16100286
|
| 说明 |
|---|
|
IHC-P
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
IHC-FoFr
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. Predicted molecular weight: 38 kDa. Block membrane in 4% BSA in Tris-buffered saline containing 0.05% Tween 20 (TBST). See Fu M et al. |
|
IHC-Fr
Use at an assay dependent concentration. See Ueberham et al. |
|
IP
Use at an assay dependent concentration. PubMed: 16100286 |
靶标
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功能
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. -
组织特异性
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. -
序列相似性
Belongs to the CCN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain. -
细胞定位
Secreted > extracellular space > extracellular matrix. Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 281103 Cow
- Entrez Gene: 1490 Human
- Entrez Gene: 14219 Mouse
- Entrez Gene: 64032 Rat
- Omim: 121009 Human
- SwissProt: O18739 Cow
- SwissProt: P29279 Human
- SwissProt: P29268 Mouse
see all -
别名
- CCN 2 antibody
- CCN family member 2 antibody
- CCN2 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (262)
ab6992 被引用在 262 文献中.
- Zhang Y et al. miR-212 promotes renal interstitial fibrosis by inhibiting hypoxia-inducible factor 1-a inhibitor. Mol Med Rep 23:N/A (2021). PubMed: 33495813
- Lyu L et al. Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress. J Cell Mol Med 25:3136-3148 (2021). PubMed: 33560596
- Zhu F et al. Tubular Numb promotes renal interstitial fibrosis via modulating HIF-1a protein stability. Biochim Biophys Acta Mol Basis Dis 1867:166081 (2021). PubMed: 33486098
- Tokuda K et al. Development of a novel knee contracture mouse model by immobilization using external fixation. Connect Tissue Res N/A:1-14 (2021). PubMed: 33602048
- Liu Y et al. Inhibiting miR-1 attenuates pulmonary arterial hypertension in rats. Mol Med Rep 23:N/A (2021). PubMed: 33604679