Anti-CRLR抗体-细胞质domain (ab140761)
Key features and details
- Rabbit polyclonal to CRLR - Cytoplasmic domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CRLR抗体-细胞质domain
参阅全部 CRLR 一抗 -
描述
兔多克隆抗体to CRLR -细胞质domain -
宿主
Rabbit -
特异性
BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except CALCR (56%). -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Rabbit, Goat, Horse, Guinea pig, Hamster, Cow, Dog, Pig, Xenopus laevis, Pufferfish, Monkey, Zebrafish, Gorilla, Opossum, Common marmoset, Orangutan, Bat, Elephant -
免疫原
A 16 amino acid synthetic peptide from the third cytoplasmic domain of Human CRLR (NP_005786.1).
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阳性对照
- Human colon tissue (submucosal plexus and submucosal vessels).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab140761于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P | (3) |
Use a concentration of 34 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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说明 |
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IHC-P
Use a concentration of 34 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
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功能
Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. -
组织特异性
Predominantly expressed in the lung and heart. -
序列相似性
Belongs to the G-protein coupled receptor 2 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 100391342 Common marmoset
- Entrez Gene: 527140 Cow
- Entrez Gene: 488438 Dog
- Entrez Gene: 100861156 Goat
- Entrez Gene: 100054281 Horse
- Entrez Gene: 10203 Human
- Entrez Gene: 54598 Mouse
- Entrez Gene: 100172095 Orangutan
see all -
别名
- Calcitonin gene related peptide type 1 receptor antibody
- Calcitonin gene-related peptide type 1 receptor antibody
- Calcitonin receptor like antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab140761 被引用在 1 文献中.
- Yoshimoto Y et al. Adrenomedullin regulates the speed of oviductal fluid flow in cattle. Mol Reprod Dev 84:712-718 (2017). PubMed: 28621496