Anti-Creatine kinase MT抗体(ab198257)
Key features and details
- Rabbit polyclonal to Creatine kinase MT
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-Creatine kinase MT抗体
参阅全部 Creatine kinase MT 一抗 -
描述
兔多克隆抗体to Creatine kinase MT -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat -
免疫原
Synthetic peptide within Human Creatine kinase MT (internal sequence). The exact sequence is proprietary.
Database link: P12532 -
阳性对照
- Mouse crassum intestinum tissue lysate, paraffin-embedded Human tonsil tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab198257于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/50 - 1/200.
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WB |
1/1000 - 1/3000. Predicted molecular weight: 47 kDa.
|
说明 |
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IHC-P
1/50 - 1/200. |
WB
1/1000 - 1/3000. Predicted molecular weight: 47 kDa. |
靶标
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相关性
Creatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. -
细胞定位
Cell Membrane and Mitochondrial -
数据库链接
- Entrez Gene: 548596 Human
- Entrez Gene: 12716 Mouse
- Entrez Gene: 29593 Rat
- Omim: 123290 Human
- Omim: 613415 Human
- SwissProt: P12532 Human
- SwissProt: P30275 Mouse
- SwissProt: P25809 Rat
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别名
- Acidic type mitochondrial creatine kinase antibody
- CKMT antibody
- CKMT1 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab198257 被引用在 1 文献中.
- Wang Y et al. Low-Dose Delta-9-Tetrahydrocannabinol as Beneficial Treatment for Aged APP/PS1 Mice. Int J Mol Sci 23:N/A (2022). PubMed: 35269905