Anti-COX2 / Cyclooxygenase 2抗体[5E10/D10] (ab701)
Key features and details
- Mouse monoclonal [5E10/D10] to COX2 / Cyclooxygenase 2
- Suitable for: WB
- Reacts with: Sheep
- Isotype: IgG1
概述
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产品名称
Anti-COX2 / Cyclooxygenase 2抗体[5E10/D10]
参阅全部 COX2 / Cyclooxygenase 2 一抗 -
描述
小鼠单克隆抗体[5E10/D10] to COX2 / Cyclooxygenase 2 -
宿主
Mouse -
特异性
COX-2. No cross-reactivity with Cox-1. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Sheep -
免疫原
Full length native protein (purified) corresponding to Human COX2/ Cyclooxygenase 2. COX-2 purified from HL-60 cells
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常规说明
Please note that we have received a report from a customer working with this antibody that they obtain two stong bands in WB (one between 40 - 50kDa and other other between 62 - 83kDa). A single band at around 72kDa is expected.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
FCS free -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
单克隆 -
克隆编号
5E10/D10 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 0.5 - 1 µg/ml.
|
说明 |
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WB
Use a concentration of 0.5 - 1 µg/ml. |
靶标
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功能
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. -
通路
Lipid metabolism; prostaglandin biosynthesis. -
序列相似性
Belongs to the prostaglandin G/H synthase family.
Contains 1 EGF-like domain. -
翻译后修饰
S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561. -
细胞定位
Microsome membrane. Endoplasmic reticulum membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 443460 Sheep
- SwissProt: P79208 Sheep
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别名
- COX 2 antibody
- COX-2 antibody
- COX2 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (0)
ab701 尚未被引用在任何文献中。