Anti-Conjugated Noradrenaline抗体(ab6454)
Key features and details
- Rabbit polyclonal to Conjugated Noradrenaline
- Suitable for: ELISA, IHC-Fr
- Reacts with: Species independent
- Isotype: IgG
概述
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产品名称
Anti-Conjugated Noradrenaline抗体 -
描述
兔多克隆抗体to Conjugated Noradrenaline -
宿主
Rabbit -
特异性
Using catecholamine-Glutaraldehyde-BSA conjugates, antibody specificity was performed with an ELISA test by competition experiments, as follows: (a) unconjugated or conjugated catecholamine concentration at half displacement (b) Non-reduced conjugateCompound Cross-reactivity ratio (a) Noradrenaline 1 Octopamine 1/31 Dopamine 1/70 Adrenaline 1/177 Noradrenaline (b) 1/316 L-DOPA, Tyramine, unconjugated Noradrenaline 1/>5000 -
经测试应用
适用于: ELISA, IHC-Frmore details -
种属反应性
与反应: Species independent -
免疫原
Synthetic noradrenaline conjugated to protein carriers (PC).
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading... -
纯度
Ammonium Sulphate Precipitation -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
Our Abpromise guarantee covers the use of ab6454 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA | ||
| IHC-Fr |
应用说明
Immunohistochemistry: 1/2000 - 1/5000. Tested using a PAP techique on free floating rat locus coeruleus.
ELISA: assay dependent.
Not tested in other applications.
Optimal dilutions / concentrations should be determined by the end user.
ELISA: assay dependent.
Not tested in other applications.
Optimal dilutions / concentrations should be determined by the end user.
靶标
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相关性
Noradrenaline (NA) is a catecholamine neurotransmitter at postganglionic sympathetic fibres, produced following a series of steps from the essential amino acid phenylalanine. Terminal postganglionic sympathetic fibres have varicosities (where NA is synthesised and stored) which form synapses with the effector organ. The adrenal medulla is a major source of catecholamines (such as NA and adrenaline), however, most of the NA produced in the adrenal medulla is converted into adrenaline. NA is key in the fight-or-flight response and also directly increases heart rate, energy release from fat, and muscle readiness.
数据表及文件
文献 (2)
ab6454 被引用在 2 文献中.
- Aschrafi A et al. Angiotensin II mediates the axonal trafficking of tyrosine hydroxylase and dopamine ß-hydroxylase mRNAs and enhances norepinephrine synthesis in primary sympathetic neurons. J Neurochem 150:666-677 (2019). PubMed: 31306490
- Arima Y et al. Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit. Elife 6:N/A (2017). PubMed: 28809157
