Clozapine N-oxide,Metabolite of Clozapine (ab141704)
Key features and details
- Metabolite of Clozapine
- CAS Number: 34233-69-7
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Clozapine N-oxide,Metabolite of Clozapine -
描述
Metabolite of Clozapine -
生物学描述
Metabolite of atypical antipsychotic Clozapine (ab120019). Active in vitro and in vivo.
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纯度
> 99% -
CAS编号
34233-69-7 -
化学结构
性能
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化学名称
8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e](1,4)diazepine N-oxide -
分子量
342.83 -
分子式
C18H19ClN4O -
PubChem识别号
36727 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2O)C=C(C=C4)Cl -
来源
Synthetic
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研究领域
相关产品
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Alternative Versions
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (22)
ab141704 被引用在 22 文献中.
- Chen L et al. Adult-born neurons in critical period maintain hippocampal seizures via local aberrant excitatory circuits. Signal Transduct Target Ther 8:225 (2023). PubMed: 37280192
- Tan N et al. Lateral Hypothalamus Calcium/Calmodulin-Dependent Protein Kinase II α Neurons Encode Novelty-Seeking Signals to Promote Predatory Eating. Research (Wash D C) 2022:9802382 (2022). PubMed: 36061821
- Zhao J et al. Activated astrocytes attenuate neocortical seizures in rodent models through driving Na+-K+-ATPase. Nat Commun 13:7136 (2022). PubMed: 36414629
- Takahashi TM et al. Optogenetic induction of hibernation-like state with modified human Opsin4 in mice. Cell Rep Methods 2:100336 (2022). PubMed: 36452866
- Horii-Hayashi N & Nishi M Protocol for behavioral tests using chemogenetically manipulated mice. STAR Protoc 2:100418 (2021). PubMed: 33899009