存放说明Shipped at 4°C. Store at 4°C (stable for up to 12 months).
存储溶液Preservative: 0.02% Sodium azide
Concentration information loading...
纯度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab106443 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 64 kDa.|
组织特异性Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.
序列相似性Contains 1 UBA domain.
Contains 1 ubiquitin-like domain.
翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
细胞定位Nucleus. Cytoplasm. Endoplasmic reticulum. May associate with the endoplasmic reticulum.
- Information by UniProt
- 28S ribosomal protein S7 antibody
- A1U antibody
- A1Up antibody
This product has been referenced in:
- Itakura E et al. Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. Mol Cell 63:21-33 (2016). WB ; Human . Read more (PubMed: 27345149) »
- Coffey RT et al. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling. J Biol Chem 291:5221-33 (2016). Read more (PubMed: 26740621) »